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tauD taurine dioxygenase [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 945021, updated on 19-Sep-2024

Summary

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Official Symbol
tauD
Official Full Name
taurine dioxygenase
Primary source
ECOCYC:EG12423
Locus tag
b0368
See related
ASAP:ABE-0001263
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK0365; ssiD; yaiG
Summary
Escherichia coli can utilize aliphatic sulfonates as sulfur sources for growth. [More information is available at EcoCyc: EG12423].
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Genomic context

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Sequence:
NC_000913.3 (387795..388646)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene taurine ABC transporter periplasmic binding protein Neighboring gene taurine ABC transporter ATP binding subunit Neighboring gene taurine ABC transporter membrane subunit Neighboring gene porphobilinogen synthase Neighboring gene pseudo Neighboring gene protein YtiB

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_000913.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. The Fe(II)/α-ketoglutarate-dependent taurine dioxygenases from Pseudomonas putida and Escherichia coli are tetramers. Knauer SH, et al. FEBS J, 2012 Mar. PMID 22221834
  2. Modular behavior of tauD provides insight into the origin of specificity in alpha-ketoglutarate-dependent nonheme iron oxygenases. McCusker KP, et al. Proc Natl Acad Sci U S A, 2009 Nov 24. PMID 19892731, Free PMC Article
  3. Probing the iron-substrate orientation for taurine/alpha-ketoglutarate dioxygenase using deuterium electron spin echo envelope modulation spectroscopy. Muthukumaran RB, et al. Biochemistry, 2007 May 22. PMID 17469855
  4. An assay for Fe(II)/2-oxoglutarate-dependent dioxygenases by enzyme-coupled detection of succinate formation. Luo L, et al. Anal Biochem, 2006 Jun 1. PMID 16643838
  5. Kinetic and spectroscopic investigation of CoII, NiII, and N-oxalylglycine inhibition of the FeII/alpha-ketoglutarate dioxygenase, TauD. Kalliri E, et al. Biochem Biophys Res Commun, 2005 Dec 9. PMID 16165092

See all (27) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Data suggest that minor active-site perturbations in tauD and alpha-ketoglutarate-dependent nonheme iron oxygenases could allow for changes in substrate reactivity while maintaining substrate triggering and oxygen binding/activation.
    Title: Modular behavior of tauD provides insight into the origin of specificity in alpha-ketoglutarate-dependent nonheme iron oxygenases.
  2. N-terminus verified by Edman degradation on mature peptide
    Title: Analysis of global responses by protein and peptide fingerprinting of proteins isolated by two-dimensional gel electrophoresis. Application to the sulfate-starvation response of Escherichia coli.
  3. The structural relationship between substrate taurine and the non-heme Fe(II) center of taurine/alpha-ketoglutarate dioxygenase (TauD) has been defined.
    Title: Probing the iron-substrate orientation for taurine/alpha-ketoglutarate dioxygenase using deuterium electron spin echo envelope modulation spectroscopy.
Submit: New GeneRIF Correction

Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Gene Ontology Provided by EcoCyc

Function Evidence Code Pubs
enables L-ascorbic acid binding IEA
Inferred from Electronic Annotation
more info
  
enables dioxygenase activity IEA
Inferred from Electronic Annotation
more info
  
enables ferrous iron binding IDA
Inferred from Direct Assay
more info
 PubMed 
enables identical protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
  
enables oxidoreductase activity IEA
Inferred from Electronic Annotation
more info
  
enables taurine dioxygenase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables taurine dioxygenase activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables taurine dioxygenase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within protein homotetramerization IPI
Inferred from Physical Interaction
more info
 PubMed 
involved_in sulfur compound metabolic process IBA
Inferred from Biological aspect of Ancestor
more info
  
acts_upstream_of_or_within sulfur compound metabolic process IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in taurine catabolic process IDA
Inferred from Direct Assay
more info
 PubMed 
Component Evidence Code Pubs
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in cytoplasm IDA
Inferred from Direct Assay
more info
 PubMed 
part_of taurine dioxygenase complex IDA
Inferred from Direct Assay
more info
 PubMed 
part_of taurine dioxygenase complex IPI
Inferred from Physical Interaction
more info
 PubMed 

General protein information

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Preferred Names
taurine dioxygenase
NP_414902.1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    387795..388646
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_414902.1 taurine dioxygenase [Escherichia coli str. K-12 substr. MG1655]

    See identical proteins and their annotated locations for NP_414902.1

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    A0A376MBM4
    Conserved Domains (1) summary
    PRK09553
    Location:3 → 279
    tauD; taurine dioxygenase; Reviewed
Nucleotide Protein
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