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OPG145 DNA helicase [ Monkeypox virus ]

Gene ID: 928993, updated on 18-Aug-2023

Summary

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Gene symbol
OPG145
Gene description
DNA helicase
Locus tag
MPXV_gp125
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Monkeypox virus (strain: Zaire-96-I-16, nat-host: Homo sapiens)
Lineage
Viruses; Varidnaviria; Bamfordvirae; Nucleocytoviricota; Pokkesviricetes; Chitovirales; Poxviridae; Chordopoxvirinae; Orthopoxvirus
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Genomic context

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Sequence:
NC_003310.1 (126230..127708)

NC_003310.1Genomic Context describing neighboring genes Neighboring gene Core protein A15 Neighboring gene Myristylated protein Neighboring gene IMV membrane protein P21 Neighboring gene Zinc finger-like protein (1) Neighboring gene IMV membrane protein A21 Neighboring gene DNA polymerase processivity factor Neighboring gene Holliday junction resolvase

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003310.1

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Human monkeypox and smallpox viruses: genomic comparison. Shchelkunov SN, et al. FEBS Lett, 2001 Nov 30. PMID 11734207, Free PMC Article
  2. Ancient Gene Capture and Recent Gene Loss Shape the Evolution of Orthopoxvirus-Host Interaction Genes. Senkevich TG, et al. mBio, 2021 Aug 31. PMID 34253028, Free PMC Article
  3. Classification of human Herpesviridae proteins using Domain-architecture Aware Inference of Orthologs (DAIO). Zmasek CM, et al. Virology, 2019 Mar. PMID 30660046, Free PMC Article

GeneRIFs: Gene References Into Functions

General protein information

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Preferred Names
DNA helicase
NP_536556.1
  • Taxonomic breadth: poxviridae; Old product: A19R; virion core associated DNA helicase; post-replicative negative transcription elongation factor; transcript release factor; similar to VACV-WR A19R and VACV-Cop A18R

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003310.1 Reference assembly

    Range
    126230..127708
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_536556.1 DNA helicase [Monkeypox virus]

    See identical proteins and their annotated locations for NP_536556.1

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    Q3I8N4, Q8V4V9
    Conserved Domains (3) summary
    smart00487
    Location:74 → 252
    DEXDc; DEAD-like helicases superfamily
    cd00046
    Location:109 → 238
    DEXDc; DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
    cl21455
    Location:310 → 416
    P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases
Protein Accession Links
GenPept Link UniProtKB Link
AAL40587.1

Gene LinkOut

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