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otsB1 trehalose-6-phosphate phosphatase OtsB [ Mycobacterium tuberculosis H37Rv ]

Gene ID: 888943, updated on 6-Oct-2023

Summary

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Gene symbol
otsB1
Gene description
trehalose-6-phosphate phosphatase OtsB
Locus tag
Rv2006
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Mycobacterium tuberculosis H37Rv (strain: H37Rv, type-material: type strain of Mycobacterium tuberculosis)
Lineage
Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex
Also known as
otsB
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Genomic context

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Sequence:
NC_000962.3 (2252002..2255985)

NC_000962.3Genomic Context describing neighboring genes Neighboring gene hypothetical protein Neighboring gene universal stress protein Neighboring gene ferredoxin Neighboring gene hypothetical protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_000962.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. The OtsAB pathway is essential for trehalose biosynthesis in Mycobacterium tuberculosis. Murphy HN, et al. J Biol Chem, 2005 Apr 15. PMID 15703182
  2. TubercuList--10 years after. Lew JM, et al. Tuberculosis (Edinb), 2011 Jan. PMID 20980199
  3. Re-annotation of the genome sequence of Mycobacterium tuberculosis H37Rv. Camus JC, et al. Microbiology (Reading), 2002 Oct. PMID 12368430
  4. Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence. Cole ST, et al. Nature, 1998 Jun 11. PMID 9634230

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. OtsA and OtsB have roles in trehalose biosynthesis in Mycobacterium tuberculosis
    Title: The OtsAB pathway is essential for trehalose biosynthesis in Mycobacterium tuberculosis.
Submit: New GeneRIF Correction

General gene information

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Homology

General protein information

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Preferred Names
trehalose-6-phosphate phosphatase OtsB
YP_177855.1
  • trehalose-phosphatase (TPP)

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000962.3 Reference assembly

    Range
    2252002..2255985
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    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. YP_177855.1 trehalose-6-phosphate phosphatase OtsB [Mycobacterium tuberculosis H37Rv]

    See identical proteins and their annotated locations for YP_177855.1

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    A0A2I7W8A4
    Conserved Domains (3) summary
    COG1554
    Location:533 → 1327
    ATH1; Trehalose and maltose hydrolase (possible phosphorylase) [Carbohydrate transport and metabolism]
    COG1877
    Location:264 → 529
    OtsB; Trehalose-6-phosphatase [Carbohydrate transport and metabolism]
    cl21460
    Location:23 → 232
    HAD_like; Haloacid Dehalogenase-like Hydrolases
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P9WN15.1

Gene LinkOut

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Molecular Biology Databases