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Rv0600c two component sensor kinase HK1 [ Mycobacterium tuberculosis H37Rv ]

Gene ID: 887847, updated on 6-Oct-2023

Summary

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Gene symbol
Rv0600c
Gene description
two component sensor kinase HK1
Locus tag
Rv0600c
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Mycobacterium tuberculosis H37Rv (strain: H37Rv, type-material: type strain of Mycobacterium tuberculosis)
Lineage
Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex
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Genomic context

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Sequence:
NC_000962.3 (697904..698410, complement)

NC_000962.3Genomic Context describing neighboring genes Neighboring gene hypothetical protein Neighboring gene ribonuclease VapC27 Neighboring gene antitoxin VapB27 Neighboring gene two component sensor kinase HK2 Neighboring gene two component DNA binding transcriptional regulator TcrA

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_000962.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Intra- and intermolecular domain interactions among novel two-component system proteins coded by Rv0600c, Rv0601c and Rv0602c of Mycobacterium tuberculosis. Shrivastava R, et al. Microbiology (Reading), 2009 Mar. PMID 19246748
  2. Probing the nucleotide binding and phosphorylation by the histidine kinase of a novel three-protein two-component system from Mycobacterium tuberculosis. Shrivastava R, et al. FEBS Lett, 2007 May 1. PMID 17434492
  3. TubercuList--10 years after. Lew JM, et al. Tuberculosis (Edinb), 2011 Jan. PMID 20980199
  4. Re-annotation of the genome sequence of Mycobacterium tuberculosis H37Rv. Camus JC, et al. Microbiology (Reading), 2002 Oct. PMID 12368430
  5. Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence. Cole ST, et al. Nature, 1998 Jun 11. PMID 9634230

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. HK1 contains an ATP-binding domain. K1 and HK2 complement each other's functions, but HK1 interacted weakly with TcrA.
    Title: Intra- and intermolecular domain interactions among novel two-component system proteins coded by Rv0600c, Rv0601c and Rv0602c of Mycobacterium tuberculosis.
  2. A new mode of interaction for phosphotransfer between the two-component system proteins in bacteria.
    Title: Probing the nucleotide binding and phosphorylation by the histidine kinase of a novel three-protein two-component system from Mycobacterium tuberculosis.
Submit: New GeneRIF Correction

General gene information

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Homology

General protein information

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Preferred Names
two component sensor kinase HK1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000962.3 Reference assembly

    Range
    697904..698410 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_215114.2 two component sensor kinase HK1 [Mycobacterium tuberculosis H37Rv]

    See identical proteins and their annotated locations for NP_215114.2

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    R4LV39
    Conserved Domains (1) summary
    COG0642
    Location:2 → 143
    BaeS; Signal transduction histidine kinase [Signal transduction mechanisms]
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
O07778.3

Gene LinkOut

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