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acg NAD(P)H nitroreductase [ Mycobacterium tuberculosis H37Rv ]

Gene ID: 887582, updated on 6-Oct-2023

Summary

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Gene symbol
acg
Gene description
NAD(P)H nitroreductase
Locus tag
Rv2032
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Mycobacterium tuberculosis H37Rv (strain: H37Rv, type-material: type strain of Mycobacterium tuberculosis)
Lineage
Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex
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Genomic context

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Sequence:
NC_000962.3 (2279129..2280124)

NC_000962.3Genomic Context describing neighboring genes Neighboring gene hypothetical protein Neighboring gene alpha-crystallin Neighboring gene hypothetical protein Neighboring gene ArsR family HTH-type transcriptional repressor Neighboring gene hypothetical protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_000962.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Mycobacterium tuberculosis acg gene is required for growth and virulence in vivo. Hu Y, et al. PLoS One, 2011. PMID 21687631, Free PMC Article
  2. Crystal structure of reduced MsAcg, a putative nitroreductase from Mycobacterium smegmatis and a close homologue of Mycobacterium tuberculosis Acg. Chauviac FX, et al. J Biol Chem, 2012 Dec 28. PMID 23148223, Free PMC Article
  3. TubercuList--10 years after. Lew JM, et al. Tuberculosis (Edinb), 2011 Jan. PMID 20980199
  4. Re-annotation of the genome sequence of Mycobacterium tuberculosis H37Rv. Camus JC, et al. Microbiology (Reading), 2002 Oct. PMID 12368430
  5. Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence. Cole ST, et al. Nature, 1998 Jun 11. PMID 9634230

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Acg from Mycobacterium smegmatis and homologue of Mycobacterium tuberculosis Acg are flavin mononucleotide -binding proteins.
    Title: Crystal structure of reduced MsAcg, a putative nitroreductase from Mycobacterium smegmatis and a close homologue of Mycobacterium tuberculosis Acg.
  2. acg encodes an essential virulence factor for M. tuberculosis and enables it to grow and survive in macrophages and in mouse organs
    Title: Mycobacterium tuberculosis acg gene is required for growth and virulence in vivo.
Submit: New GeneRIF Correction

General gene information

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Homology

General protein information

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Preferred Names
NAD(P)H nitroreductase
NP_216548.1
  • acr-coregulated gene

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000962.3 Reference assembly

    Range
    2279129..2280124
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_216548.1 NAD(P)H nitroreductase [Mycobacterium tuberculosis H37Rv]

    See identical proteins and their annotated locations for NP_216548.1

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    A0A0U0SB09
    Conserved Domains (1) summary
    PRK07877
    Location:9 → 322
    PRK07877; Rv1355c family protein
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P9WIZ9.1

Gene LinkOut

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