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norC nitric oxide reductase subunit C [ Pseudomonas aeruginosa PAO1 ]

Gene ID: 882200, updated on 11-Sep-2024

Summary

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Gene symbol
norC
Gene description
nitric oxide reductase subunit C
Locus tag
PA0523
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Pseudomonas aeruginosa PAO1 (strain: PAO1)
Lineage
Bacteria; Pseudomonadota; Gammaproteobacteria; Pseudomonadales; Pseudomonadaceae; Pseudomonas
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Genomic context

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Sequence:
NC_002516.2 (582015..582455)

NC_002516.2Genomic Context describing neighboring genes Neighboring gene cytochrome C oxidase subunit Neighboring gene hypothetical protein Neighboring gene nitric oxide reductase subunit B Neighboring gene denitrification protein NorD Neighboring gene hypothetical protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_002516.2

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Pseudomonas aeruginosa overexpression system of nitric oxide reductase for in vivo and in vitro mutational analyses. Yamagiwa R, et al. Biochim Biophys Acta Bioenerg, 2018 May. PMID 29499184
  2. Effect of Outer-Sphere Side Chain Substitutions on the Fate of the trans Iron-Nitrosyl Dimer in Heme/Nonheme Engineered Myoglobins (Fe(B)Mbs): Insights into the Mechanism of Denitrifying NO Reductases. Matsumura H, et al. Biochemistry, 2016 Apr 12. PMID 27003474, Free PMC Article
  3. Molecular structure and function of bacterial nitric oxide reductase. Hino T, et al. Biochim Biophys Acta, 2012 Apr. PMID 22001779
  4. Structural basis of biological N2O generation by bacterial nitric oxide reductase. Hino T, et al. Science, 2010 Dec 17. PMID 21109633
  5. Pseudomonas Genome Database: facilitating user-friendly, comprehensive comparisons of microbial genomes. Winsor GL, et al. Nucleic Acids Res, 2009 Jan. PMID 18978025, Free PMC Article

See all (14) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Pseudomonas aeruginosa overexpression system of nitric oxide reductase for in vivo and in vitro mutational analyses.
    Title: Pseudomonas aeruginosa overexpression system of nitric oxide reductase for in vivo and in vitro mutational analyses.
  2. Data suggest adding hydrophilicity (such as in I107E mutation) to distal pocket is at origin of increase in nitric oxide reductase (NOR) activity in sperm whale myoglobin; proton transfer appears important in biocatalysis by P. aeruginosa NOR subunit C.
    Title: Effect of Outer-Sphere Side Chain Substitutions on the Fate of the trans Iron-Nitrosyl Dimer in Heme/Nonheme Engineered Myoglobins (Fe(B)Mbs): Insights into the Mechanism of Denitrifying NO Reductases.
  3. Studies indicate that the structure of nitric oxide reductase cNOR provides insights into its structural and functional properties.
    Title: Molecular structure and function of bacterial nitric oxide reductase.
  4. crystal structure of NOR at 2.7 A; structure reveals details of catalytic binuclear center; non-heme iron is coordinated by 3 His and 1 Glu ligands; this structural characteristic is crucial for NOR reaction
    Title: Structural basis of biological N2O generation by bacterial nitric oxide reductase.
Submit: New GeneRIF Correction

General gene information

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Homology

General protein information

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Preferred Names
nitric oxide reductase subunit C
NP_249214.1
  • Product name confidence: class 1 (Function experimentally demonstrated in P. aeruginosa)

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_002516.2 Reference assembly

    Range
    582015..582455
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_249214.1 nitric oxide reductase subunit C [Pseudomonas aeruginosa PAO1]

    See identical proteins and their annotated locations for NP_249214.1

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    Q59646
    Conserved Domains (1) summary
    pfam00034
    Location:49 → 133
    Cytochrom_C; Cytochrome c
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q59646.3

Gene LinkOut

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Research Materials