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gyrB DNA gyrase subunit B [ Pseudomonas aeruginosa PAO1 ]

Gene ID: 879230, updated on 24-Aug-2024

Summary

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Gene symbol
gyrB
Gene description
DNA gyrase subunit B
Locus tag
PA0004
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Pseudomonas aeruginosa PAO1 (strain: PAO1)
Lineage
Bacteria; Pseudomonadota; Gammaproteobacteria; Pseudomonadales; Pseudomonadaceae; Pseudomonas
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Genomic context

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Sequence:
NC_002516.2 (4275..6695)

NC_002516.2Genomic Context describing neighboring genes Neighboring gene chromosome replication initiator DnaA Neighboring gene DNA polymerase III subunit beta Neighboring gene DNA replication and repair protein RecF Neighboring gene lysophosphatidic acid acyltransferase Neighboring gene D-glycero-beta-D-manno-heptose-1,7-bisphosphate 7-phosphatase

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_002516.2

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. The bacteriophage LUZ24 "Igy" peptide inhibits the Pseudomonas DNA gyrase. De Smet J, et al. Cell Rep, 2021 Aug 24. PMID 34433028
  2. Hydrolysis of ATP at only one GyrB subunit is sufficient to promote supercoiling by DNA gyrase. Kampranis SC, et al. J Biol Chem, 1998 Oct 9. PMID 9756859
  3. DNA supercoiling in gyrase mutants. Steck TR, et al. J Bacteriol, 1984 May. PMID 6327603, Free PMC Article
  4. The binding of gyrase to DNA: analysis by retention by nitrocellulose filters. Higgins NP, et al. Nucleic Acids Res, 1982 Nov 11. PMID 6294616, Free PMC Article
  5. Energy coupling in DNA gyrase and the mechanism of action of novobiocin. Sugino A, et al. Proc Natl Acad Sci U S A, 1978 Oct. PMID 368801, Free PMC Article

See all (16) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. The bacteriophage LUZ24 ""Igy"" peptide inhibits the Pseudomonas DNA gyrase.
    Title: The bacteriophage LUZ24 "Igy" peptide inhibits the Pseudomonas DNA gyrase.
Submit: New GeneRIF Correction

General gene information

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Homology

Gene Ontology Provided by PseudoCAP

Function Evidence Code Pubs
enables ATP binding ISS
Inferred from Sequence or Structural Similarity
more info
 PubMed 
enables DNA binding ISS
Inferred from Sequence or Structural Similarity
more info
 PubMed 
enables DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity ISS
Inferred from Sequence or Structural Similarity
more info
 PubMed 
Process Evidence Code Pubs
acts_upstream_of_or_within DNA topological change ISS
Inferred from Sequence or Structural Similarity
more info
 PubMed 
acts_upstream_of_or_within DNA-templated transcription ISS
Inferred from Sequence or Structural Similarity
more info
 PubMed 

General protein information

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Preferred Names
DNA gyrase subunit B
NP_064724.1
  • Product name confidence: class 2 (High similarity to functionally studied protein)

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_002516.2 Reference assembly

    Range
    4275..6695
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_064724.1 DNA gyrase subunit B [Pseudomonas aeruginosa PAO1]

    See identical proteins and their annotated locations for NP_064724.1

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    Q9S1C7
    Conserved Domains (1) summary
    PRK14939
    Location:1 → 806
    gyrB; DNA gyrase subunit B; Provisional
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9I7C2.1

Gene LinkOut

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Molecular Biology Databases