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ddlA D-alanine--D-alanine ligase [ Pseudomonas aeruginosa PAO1 ]

Gene ID: 879033, updated on 10-Oct-2024

Summary

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Gene symbol
ddlA
Gene description
D-alanine--D-alanine ligase
Locus tag
PA4201
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Pseudomonas aeruginosa PAO1 (strain: PAO1)
Lineage
Bacteria; Pseudomonadota; Gammaproteobacteria; Pseudomonadales; Pseudomonadaceae; Pseudomonas
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Genomic context

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Sequence:
NC_002516.2 (4700906..4701946, complement)

NC_002516.2Genomic Context describing neighboring genes Neighboring gene acyl-CoA dehydrogenase Neighboring gene hypothetical protein Neighboring gene hypothetical protein Neighboring gene transcriptional regulator

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_002516.2

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. D-alanine: D-alanine ligase of Escherichia coli. Expression, purification and inhibitory studies on the cloned enzyme. al-Bar OA, et al. Biochem J, 1992 Mar 15. PMID 1554356, Free PMC Article
  2. Pseudomonas Genome Database: facilitating user-friendly, comprehensive comparisons of microbial genomes. Winsor GL, et al. Nucleic Acids Res, 2009 Jan. PMID 18978025, Free PMC Article
  3. Defining the Pseudomonas aeruginosa SOS response and its role in the global response to the antibiotic ciprofloxacin. Cirz RT, et al. J Bacteriol, 2006 Oct. PMID 17015649, Free PMC Article
  4. Cystic fibrosis sputum supports growth and cues key aspects of Pseudomonas aeruginosa physiology. Palmer KL, et al. J Bacteriol, 2005 Aug. PMID 16030221, Free PMC Article
  5. A cystic fibrosis epidemic strain of Pseudomonas aeruginosa displays enhanced virulence and antimicrobial resistance. Salunkhe P, et al. J Bacteriol, 2005 Jul. PMID 15995206, Free PMC Article

See all (11) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by PseudoCAP

Function Evidence Code Pubs
enables D-alanine-D-alanine ligase activity ISS
Inferred from Sequence or Structural Similarity
more info
 PubMed 
Process Evidence Code Pubs
acts_upstream_of_or_within peptidoglycan biosynthetic process ISS
Inferred from Sequence or Structural Similarity
more info
 PubMed 

General protein information

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Preferred Names
D-alanine--D-alanine ligase
NP_252890.1
  • Product name confidence: class 2 (High similarity to functionally studied protein)

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_002516.2 Reference assembly

    Range
    4700906..4701946 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_252890.1 D-alanine--D-alanine ligase [Pseudomonas aeruginosa PAO1]

    See identical proteins and their annotated locations for NP_252890.1

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    Q9HWI0
    Conserved Domains (1) summary
    PRK01372
    Location:2 → 330
    ddl; D-alanine--D-alanine ligase; Reviewed
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9HWI0.1

Gene LinkOut

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Molecular Biology Databases
Research Materials