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IES6 Ies6p [ Saccharomyces cerevisiae S288C ]

Gene ID: 856667, updated on 2-Nov-2024

Summary

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Official Symbol
IES6
Official Full Name
Ies6p
Primary source
SGD:S000000770
Locus tag
YEL044W
See related
AllianceGenome:SGD:S000000770; FungiDB:YEL044W; VEuPathDB:YEL044W
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Summary
Predicted to be involved in chromatin remodeling. Located in nucleus. Part of Ino80 complex. Orthologous to human INO80C (INO80 complex subunit C). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See IES6 in Genome Data Viewer
Location:
chromosome: V
Exon count:
1
Sequence:
Chromosome: V; NC_001137.3 (69757..70257)

Chromosome V - NC_001137.3Genomic Context describing neighboring genes Neighboring gene fumarate reductase Neighboring gene threonine aldolase GLY1 Neighboring gene Gta1p Neighboring gene guanosine diphosphatase

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_001137.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Regulation of telomere structure and functions by subunits of the INO80 chromatin remodeling complex. Yu EY, et al. Mol Cell Biol, 2007 Aug. PMID 17562861, Free PMC Article
  2. The INO80 chromatin remodeling complex prevents polyploidy and maintains normal chromatin structure at centromeres. Chambers AL, et al. Genes Dev, 2012 Dec 1. PMID 23207916, Free PMC Article
  3. The INO80 chromatin remodeler sustains metabolic stability by promoting TOR signaling and regulating histone acetylation. Beckwith SL, et al. PLoS Genet, 2018 Feb. PMID 29462149, Free PMC Article
  4. The budding yeast RSC complex maintains ploidy by promoting spindle pole body insertion. Sing TL, et al. J Cell Biol, 2018 Jul 2. PMID 29875260, Free PMC Article
  5. Cycloheximide Inhibits Actin Cytoskeletal Dynamics by Suppressing Signaling via RhoA. Darvishi E, et al. J Cell Biochem, 2016 Dec. PMID 27192630

See all (57) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by SGD

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
  
involved_in chromatin remodeling IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in chromatin remodeling IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
part_of Ino80 complex IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of Ino80 complex IEA
Inferred from Electronic Annotation
more info
  
part_of Ino80 complex IPI
Inferred from Physical Interaction
more info
 PubMed 
located_in nucleus HDA PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
Ies6p
NP_010870.1
  • Component of the INO80 chromatin remodeling complex; critical for INO80 function; involved in regulation of chromosome segregation and maintenance of normal centromeric chromatin structure; human ortholog INO80C is a member of the human INO80 complex; implicated in DNA repair based on genetic interactions with RAD52 epistasis genes

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001137.3 Reference assembly

    Range
    69757..70257
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001178859.1 → NP_010870.1  TPA: Ies6p [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_010870.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    D3DLK5, P32617, Q6Q5Q5
    UniProtKB/TrEMBL
    A6ZQQ6, B3LRX2, C7GKE7, C8Z6V0, G2WCI9, N1P592
    Conserved Domains (1) summary
    cl02154
    Location:44 → 166
    YL1_C; YL1 nuclear protein C-terminal domain
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P32617.1

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