TCA17 Tca17p [Saccharomyces cerevisiae S288C] - Gene

Summary

Official Symbol: TCA17
Official Full Name: Tca17p
Primary source: SGD:S000000774
Locus tag: YEL048C
See related: AllianceGenome:SGD:S000000774; FungiDB:YEL048C; VEuPathDB:YEL048C
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Saccharomyces cerevisiae S288C (strain: S288C)
Lineage: Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Summary: Involved in early endosome to Golgi transport and protein-containing complex assembly. Located in Golgi apparatus. Part of TRAPPII protein complex. Used to study myoclonic-atonic epilepsy and rhabdomyolysis-myalgia syndrome. [provided by Alliance of Genome Resources, Nov 2024]
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Chromosome V - NC_001137.3 Genomic Context describing neighboring genes

Go to nucleotide: Graphics FASTA GenBank

The three-dimensional structure of yeast Tca17.
Title: Crystal structure of the yeast TRAPP-associated protein Tca17.

Submit: New GeneRIF Correction

Products	Interactant	Other Gene	Complex	Source	Pubs	Description

Function	Evidence Code	Pubs
enables molecular_function	ND No biological Data available more info

Process	Evidence Code	Pubs
involved_in early endosome to Golgi transport	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in endoplasmic reticulum to Golgi vesicle-mediated transport	IBA Inferred from Biological aspect of Ancestor more info
involved_in endoplasmic reticulum to Golgi vesicle-mediated transport	IEA Inferred from Electronic Annotation more info
involved_in protein-containing complex assembly	IMP Inferred from Mutant Phenotype more info	PubMed

Component	Evidence Code	Pubs
located_in Golgi apparatus	IDA Inferred from Direct Assay more info	PubMed
located_in Golgi apparatus	IEA Inferred from Electronic Annotation more info
part_of TRAPP complex	IBA Inferred from Biological aspect of Ancestor more info
part_of TRAPPII protein complex	IDA Inferred from Direct Assay more info	PubMed
is_active_in cytoplasm	IBA Inferred from Biological aspect of Ancestor more info
located_in cytosol	HDA more info	PubMed
is_active_in nucleus	IBA Inferred from Biological aspect of Ancestor more info
part_of protein-containing complex	IEA Inferred from Electronic Annotation more info

NP_010866.1

Component of transport protein particle (TRAPP) complex II; TRAPPII is a multimeric guanine nucleotide-exchange factor for the GTPase Ypt1p, regulating intra-Golgi and endosome-Golgi traffic; promotes association of TRAPPII-specific subunits with the TRAPP core complex; sedlin related; human Sedlin mutations cause SEDT, a skeletal disorder