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CRP1 Crp1p [ Saccharomyces cerevisiae S288C ]

Gene ID: 856551, updated on 2-Nov-2024

Summary

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Official Symbol
CRP1
Official Full Name
Crp1p
Primary source
SGD:S000001189
Locus tag
YHR146W
See related
AllianceGenome:SGD:S000001189; FungiDB:YHR146W; VEuPathDB:YHR146W
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Summary
Enables DNA binding activity. Predicted to be involved in signal transduction. Is active in cell periphery. [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See CRP1 in Genome Data Viewer
Location:
chromosome: VIII
Exon count:
1
Sequence:
Chromosome: VIII; NC_001140.6 (390300..391697)

Chromosome VIII - NC_001140.6Genomic Context describing neighboring genes Neighboring gene deoxycytidine monophosphate deaminase Neighboring gene tRNA-Pro Neighboring gene mitochondrial 54S ribosomal protein YmL16 Neighboring gene snoRNA-binding rRNA-processing protein IMP3

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_001140.6

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Crp1p, a new cruciform DNA-binding protein in the yeast Saccharomyces cerevisiae. Rass U, et al. J Mol Biol, 2002 Nov 1. PMID 12419258
  2. Atg45 is an autophagy receptor for glycogen, a non-preferred cargo of bulk autophagy in yeast. Isoda T, et al. iScience, 2024 Jun 21. PMID 38832010, Free PMC Article
  3. The cruciform DNA-binding protein Crp1 stimulates the endonuclease activity of Mus81-Mms4 in Saccharomyces cerevisiae. Phung HTT, et al. FEBS Lett, 2020 Dec. PMID 32936932
  4. An FHA domain-mediated protein interaction network of Rad53 reveals its role in polarized cell growth. Smolka MB, et al. J Cell Biol, 2006 Dec 4. PMID 17130285, Free PMC Article
  5. α-Synuclein Decreases the Abundance of Proteasome Subunits and Alters Ubiquitin Conjugates in Yeast. Popova B, et al. Cells, 2021 Aug 28. PMID 34571878, Free PMC Article

See all (34) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. The cruciform DNA-binding protein Crp1 stimulates the endonuclease activity of Mus81-Mms4 in Saccharomyces cerevisiae.
    Title: The cruciform DNA-binding protein Crp1 stimulates the endonuclease activity of Mus81-Mms4 in Saccharomyces cerevisiae.
Submit: New GeneRIF Correction

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by SGD

Function Evidence Code Pubs
enables DNA binding IDA
Inferred from Direct Assay
more info
 PubMed 
enables DNA binding IEA
Inferred from Electronic Annotation
more info
  
enables protein kinase binding IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
  
involved_in signal transduction IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in cell periphery IDA
Inferred from Direct Assay
more info
 PubMed 
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of nucleotide-activated protein kinase complex IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in nucleus IC
Inferred by Curator
more info
 PubMed 

General protein information

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Preferred Names
Crp1p
NP_012016.1
  • Protein that binds to cruciform DNA structures; CRP1 has a paralog, MDG1, that arose from the whole genome duplication

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001140.6 Reference assembly

    Range
    390300..391697
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001179277.1 → NP_012016.1  TPA: Crp1p [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_012016.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    A6ZT54, B3LSR0, D3DL95, P38845
    UniProtKB/TrEMBL
    G2WFL9, N1P176
    Conserved Domains (2) summary
    cd02859
    Location:8 → 90
    E_set_AMPKbeta_like_N; N-terminal Early set domain, a glycogen binding domain, associated with the catalytic domain of AMP-activated protein kinase beta subunit
    NF033645
    Location:215 → 385
    pilus_FilE; putative pilus assembly protein FilE
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P38845.1

Gene LinkOut

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