U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

RPS27B [ Saccharomyces cerevisiae S288C ]

Gene ID: 856415, updated on 11-Sep-2024

Summary

Go to the top of the page Help
Official Symbol
RPS27B
Primary source
SGD:S000001063
Locus tag
YHR021C
See related
AllianceGenome:SGD:S000001063; FungiDB:YHR021C; VEuPathDB:YHR021C
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Summary
A structural constituent of ribosome. Involved in endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); and ribosomal small subunit assembly. Part of cytosolic small ribosomal subunit. Human ortholog(s) of this gene implicated in Diamond-Blackfan anemia 17. Orthologous to several human genes including RPS27 (ribosomal protein S27). [provided by Alliance of Genome Resources, Apr 2022]
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
Location:
chromosome: VIII
Exon count:
2
Sequence:
Chromosome: VIII; NC_001140.6 (147871..148669, complement)

Chromosome VIII - NC_001140.6Genomic Context describing neighboring genes Neighboring gene proline--tRNA ligase Neighboring gene tRNA-Ala Neighboring gene Ecm12p Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein

Genomic regions, transcripts, and products

Go to the top of the page Help
Genomic Sequence:
NC_001140.6

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. Functional analysis of Rrp7p, an essential yeast protein involved in pre-rRNA processing and ribosome assembly. Baudin-Baillieu A, et al. Mol Cell Biol, 1997 Sep. PMID 9271380, Free PMC Article
  2. Genetic and biochemical characterization of antisuppressor mutants in the yeast Saccharomyces cerevisiae. Ishiguro J. Curr Genet, 1981 Dec. PMID 24185993
  3. The Gcn4 transcription factor reduces protein synthesis capacity and extends yeast lifespan. Mittal N, et al. Nat Commun, 2017 Sep 6. PMID 28878244, Free PMC Article
  4. Genome-wide binding map of the histone deacetylase Rpd3 in yeast. Kurdistani SK, et al. Nat Genet, 2002 Jul. PMID 12089521
  5. Protein topography of the 40 S ribosomal subunit from Saccharomyces cerevisiae as shown by chemical cross-linking. Yeh YC, et al. J Biol Chem, 1986 Oct 25. PMID 3533916

See all (69) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

Go to the top of the page Help
Products Interactant Other Gene Complex Source Pubs Description

General gene information

Go to the top of the page Help

Markers

Homology

Gene Ontology Provided by SGD

Function Evidence Code Pubs
enables RNA binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
  
enables structural constituent of ribosome IBA
Inferred from Biological aspect of Ancestor
more info
  
enables structural constituent of ribosome IDA
Inferred from Direct Assay
more info
 PubMed 
enables structural constituent of ribosome IEA
Inferred from Electronic Annotation
more info
  
enables zinc ion binding RCA
inferred from Reviewed Computational Analysis
more info
 PubMed 
Process Evidence Code Pubs
involved_in endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) IGI
Inferred from Genetic Interaction
more info
 PubMed 
involved_in ribosomal small subunit assembly IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in ribosomal small subunit assembly IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in translation IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  
part_of cytosolic small ribosomal subunit IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of cytosolic small ribosomal subunit IDA
Inferred from Direct Assay
more info
 PubMed 
part_of ribonucleoprotein complex IEA
Inferred from Electronic Annotation
more info
  
part_of ribosomal subunit IEA
Inferred from Electronic Annotation
more info
  
located_in ribosome IEA
Inferred from Electronic Annotation
more info
  

General protein information

Go to the top of the page Help
Preferred Names
ribosomal 40S subunit protein S27B
NP_011885.1
  • Protein component of the small (40S) ribosomal subunit; homologous to mammalian ribosomal protein S27, no bacterial homolog; RPS27B has a paralog, RPS27A, that arose from the whole genome duplication

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001140.6 Reference assembly

    Range
    147871..148669 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001179151.1 → NP_011885.1  TPA: ribosomal 40S subunit protein S27B [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_011885.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    D3DKW6, P38711
    UniProtKB/TrEMBL
    A6ZSS5, C8ZA88, G2WF90
    Conserved Domains (1) summary
    PTZ00083
    Location:5 → 82
    PTZ00083; 40S ribosomal protein S27; Provisional
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P38711.1

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Other Literature Sources
Molecular Biology Databases
Research Materials
Tools
Miscellaneous