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MRP4 mitochondrial 37S ribosomal protein MRP4 [ Saccharomyces cerevisiae S288C ]

Gene ID: 856384, updated on 2-Nov-2024

Summary

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Official Symbol
MRP4
Official Full Name
mitochondrial 37S ribosomal protein MRP4
Primary source
SGD:S000000996
Locus tag
YHL004W
See related
AllianceGenome:SGD:S000000996; FungiDB:YHL004W; VEuPathDB:YHL004W
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Also known as
uS2m
Summary
A structural constituent of ribosome. Predicted to be involved in mitochondrial translation. Located in mitochondrion. Part of mitochondrial small ribosomal subunit. Human ortholog(s) of this gene implicated in combined oxidative phosphorylation deficiency 36. Orthologous to human MRPS2 (mitochondrial ribosomal protein S2). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See MRP4 in Genome Data Viewer
Location:
chromosome: VIII
Exon count:
1
Sequence:
Chromosome: VIII; NC_001140.6 (99219..100403)

Chromosome VIII - NC_001140.6Genomic Context describing neighboring genes Neighboring gene mitogen-activated protein kinase kinase kinase kinase STE20 Neighboring gene Shu1p Neighboring gene uncharacterized protein Neighboring gene sphingosine N-acyltransferase LAG1 Neighboring gene ESCRT-0 subunit protein HSE1

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_001140.6

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Characterization of a yeast mitochondrial ribosomal protein structurally related to the mammalian 68-kDa high affinity laminin receptor. Davis SC, et al. J Biol Chem, 1992 Mar 15. PMID 1531984
  2. Identification of 12 new yeast mitochondrial ribosomal proteins including 6 that have no prokaryotic homologues. Saveanu C, et al. J Biol Chem, 2001 May 11. PMID 11278769
  3. Tag-mediated isolation of yeast mitochondrial ribosome and mass spectrometric identification of its new components. Gan X, et al. Eur J Biochem, 2002 Nov. PMID 12392552
  4. Mdm38 interacts with ribosomes and is a component of the mitochondrial protein export machinery. Frazier AE, et al. J Cell Biol, 2006 Feb 13. PMID 16476776, Free PMC Article
  5. MitoStores: chaperone-controlled protein granules store mitochondrial precursors in the cytosol. Krämer L, et al. EMBO J, 2023 Apr 3. PMID 36704946, Free PMC Article

See all (46) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by SGD

Function Evidence Code Pubs
enables structural constituent of ribosome IBA
Inferred from Biological aspect of Ancestor
more info
  
enables structural constituent of ribosome IDA
Inferred from Direct Assay
more info
 PubMed 
enables structural constituent of ribosome IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in mitochondrial translation IC
Inferred by Curator
more info
 PubMed 
involved_in translation IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
part_of mitochondrial small ribosomal subunit IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of mitochondrial small ribosomal subunit IDA
Inferred from Direct Assay
more info
 PubMed 
located_in mitochondrion HDA PubMed 
located_in mitochondrion IEA
Inferred from Electronic Annotation
more info
  
part_of ribonucleoprotein complex IEA
Inferred from Electronic Annotation
more info
  
located_in ribosome IEA
Inferred from Electronic Annotation
more info
  
part_of small ribosomal subunit IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
mitochondrial 37S ribosomal protein MRP4
NP_011859.1
  • Mitochondrial ribosomal protein of the small subunit

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001140.6 Reference assembly

    Range
    99219..100403
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001179084.1 → NP_011859.1  TPA: mitochondrial 37S ribosomal protein MRP4 [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_011859.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    D3DKR0, P32902
    UniProtKB/TrEMBL
    A6ZSP8, B3LSB4, B5VJS4, C7GX98, C8ZA61, G2WF62, N1P348
    Conserved Domains (1) summary
    pfam00318
    Location:188 → 383
    Ribosomal_S2; Ribosomal protein S2
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P32902.1

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