GOS1 Gos1p [Saccharomyces cerevisiae S288C] - Gene

Summary

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Official Symbol: GOS1
Official Full Name: Gos1p
Primary source: SGD:S000001023
Locus tag: YHL031C
See related: AllianceGenome:SGD:S000001023; FungiDB:YHL031C; VEuPathDB:YHL031C
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Saccharomyces cerevisiae S288C (strain: S288C)
Lineage: Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Summary: Enables SNAP receptor activity. Involved in Golgi vesicle transport and vesicle fusion. Located in Golgi medial cisterna. Part of SNARE complex. Orthologous to human GOSR1 (golgi SNAP receptor complex member 1). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See GOS1 in Genome Data Viewer

Location:: chromosome: VIII

Exon count:: 1

Sequence:: Chromosome: VIII; NC_001140.6 (38815..39486, complement)

Chromosome VIII - NC_001140.6 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_001140.6

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

The crystal structure of the truncated forms of Gos1 has been determined.
Title: Crystallization and preliminary X-ray diffraction analysis of Gos1p, a yeast SNARE protein.

Submit: New GeneRIF Correction

Pathways from PubChem

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Homology

Orthologs from OrthoDB

Gene Ontology Provided by SGD

Function	Evidence Code	Pubs
enables SNAP receptor activity	IBA Inferred from Biological aspect of Ancestor more info
enables SNAP receptor activity	IDA Inferred from Direct Assay more info	PubMed

Process	Evidence Code	Pubs
involved_in Golgi vesicle transport	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in endoplasmic reticulum to Golgi vesicle-mediated transport	IBA Inferred from Biological aspect of Ancestor more info
involved_in endoplasmic reticulum to Golgi vesicle-mediated transport	IEA Inferred from Electronic Annotation more info
involved_in inter-Golgi cisterna vesicle-mediated transport	IBA Inferred from Biological aspect of Ancestor more info
involved_in protein transport	IEA Inferred from Electronic Annotation more info
involved_in vesicle fusion	IBA Inferred from Biological aspect of Ancestor more info
involved_in vesicle fusion	IDA Inferred from Direct Assay more info	PubMed
involved_in vesicle-mediated transport	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in Golgi apparatus	IEA Inferred from Electronic Annotation more info
is_active_in Golgi medial cisterna	IBA Inferred from Biological aspect of Ancestor more info
located_in Golgi medial cisterna	IDA Inferred from Direct Assay more info	PubMed
is_active_in Golgi membrane	IBA Inferred from Biological aspect of Ancestor more info
located_in Golgi membrane	IEA Inferred from Electronic Annotation more info
part_of SNARE complex	IBA Inferred from Biological aspect of Ancestor more info
part_of SNARE complex	IDA Inferred from Direct Assay more info	PubMed
located_in cis-Golgi network	IEA Inferred from Electronic Annotation more info
located_in membrane	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: Gos1p

NP_011832.1

v-SNARE protein involved in Golgi transport; homolog of the mammalian protein GOS-28/GS28

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

NC_001140.6 Reference assembly

Range

38815..39486 complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NM_001179111.1 → NP_011832.1 TPA: Gos1p [Saccharomyces cerevisiae S288C]

See identical proteins and their annotated locations for NP_011832.1

Status: REVIEWED

UniProtKB/Swiss-Prot

D3DKT7, P38736

UniProtKB/TrEMBL

A6ZSL9, B3LS88, B5VJP8, C7GIQ5, G2WF34, N1P237

Conserved Domains (1) summary

pfam12352
Location:136 → 201

V-SNARE_C; Snare region anchored in the vesicle membrane C-terminus