U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

RGC1 Rgc1p [ Saccharomyces cerevisiae S288C ]

Gene ID: 856231, updated on 2-Nov-2024

Summary

Go to the top of the page Help
Official Symbol
RGC1
Official Full Name
Rgc1p
Primary source
SGD:S000006319
Locus tag
YPR115W
See related
AllianceGenome:SGD:S000006319; FungiDB:YPR115W; VEuPathDB:YPR115W
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Summary
Predicted to enable channel regulator activity. Involved in positive regulation of glycerol transport. Located in cytoplasm. [provided by Alliance of Genome Resources, Nov 2024]
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
See RGC1 in Genome Data Viewer
Location:
chromosome: XVI
Exon count:
1
Sequence:
Chromosome: XVI; NC_001148.4 (754877..758128)

Chromosome XVI - NC_001148.4Genomic Context describing neighboring genes Neighboring gene CDP-diacylglycerol--inositol 3-phosphatidyltransferase Neighboring gene uncharacterized protein Neighboring gene Rrg8p Neighboring gene Hob2p

Genomic regions, transcripts, and products

Go to the top of the page Help
Genomic Sequence:
NC_001148.4

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. Yeast Fps1 glycerol facilitator functions as a homotetramer. Beese-Sims SE, et al. Yeast, 2011 Dec. PMID 22030956, Free PMC Article
  2. Rgc2 Regulator of Glycerol Channel Fps1 Functions as a Homo- and Heterodimer with Rgc1. Lee J, et al. Eukaryot Cell, 2015 Jul. PMID 26024902, Free PMC Article
  3. Identification of positive regulators of the yeast fps1 glycerol channel. Beese SE, et al. PLoS Genet, 2009 Nov. PMID 19956799, Free PMC Article
  4. MAPK Hog1 closes the S. cerevisiae glycerol channel Fps1 by phosphorylating and displacing its positive regulators. Lee J, et al. Genes Dev, 2013 Dec 1. PMID 24298058, Free PMC Article
  5. Mapping protein-protein interactions for the yeast ABC transporter Ycf1p by integrated split-ubiquitin membrane yeast two-hybrid analysis. Paumi CM, et al. Mol Cell, 2007 Apr 13. PMID 17434123

See all (50) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

Go to the top of the page Help
Products Interactant Other Gene Complex Source Pubs Description

General gene information

Go to the top of the page Help

Homology

Gene Ontology Provided by SGD

Function Evidence Code Pubs
enables channel regulator activity ISS
Inferred from Sequence or Structural Similarity
more info
 PubMed 
Process Evidence Code Pubs
involved_in positive regulation of glycerol transport IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm HDA PubMed 
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  

General protein information

Go to the top of the page Help
Preferred Names
Rgc1p
NP_015440.1
  • Putative regulator of the Fps1p glycerol channel; multiply phosphorylated by Hog1p under osmotic stress; contains a pleckstrin homology domain; forms homodimers and heterodimerizes with paralog Ask10p; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001148.4 Reference assembly

    Range
    754877..758128
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001184212.1 → NP_015440.1  TPA: Rgc1p [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_015440.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    D6W4B4, Q06108
    UniProtKB/TrEMBL
    A6ZWZ6, B3LK79, C8ZJD7, N1NWG4
    Conserved Domains (1) summary
    cl17171
    Location:496 → 535
    PH-like; Pleckstrin homology-like domain
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q06108.1

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Other Literature Sources
Molecular Biology Databases
Research Materials
Tools