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RDS3 U2 snRNP complex subunit RDS3 [ Saccharomyces cerevisiae S288C ]

Gene ID: 856209, updated on 18-Sep-2024

Summary

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Official Symbol
RDS3
Official Full Name
U2 snRNP complex subunit RDS3
Primary source
SGD:S000006298
Locus tag
YPR094W
See related
AllianceGenome:SGD:S000006298; FungiDB:YPR094W; VEuPathDB:YPR094W
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Summary
Involved in response to xenobiotic stimulus and spliceosomal complex assembly. Part of U2 snRNP. Orthologous to human PHF5A (PHD finger protein 5A). [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

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See RDS3 in Genome Data Viewer
Location:
chromosome: XVI
Exon count:
1
Sequence:
Chromosome: XVI; NC_001148.4 (720637..720960)

Chromosome XVI - NC_001148.4Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene ubiquitin-protein ligase ASR1 Neighboring gene Arf family guanine nucleotide exchange factor SYT1 Neighboring gene uncharacterized protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_001148.4

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Solution structure of the U2 snRNP protein Rds3p reveals a knotted zinc-finger motif. van Roon AM, et al. Proc Natl Acad Sci U S A, 2008 Jul 15. PMID 18621724, Free PMC Article
  2. Rds3p is required for stable U2 snRNP recruitment to the splicing apparatus. Wang Q, et al. Mol Cell Biol, 2003 Oct. PMID 14517302, Free PMC Article
  3. New regulators of drug sensitivity in the family of yeast zinc cluster proteins. Akache B, et al. J Biol Chem, 2002 Jun 14. PMID 11943786
  4. Molecular architecture of the Saccharomyces cerevisiae activated spliceosome. Rauhut R, et al. Science, 2016 Sep 23. PMID 27562955
  5. Proteomic analysis identifies a new complex required for nuclear pre-mRNA retention and splicing. Dziembowski A, et al. EMBO J, 2004 Dec 8. PMID 15565172, Free PMC Article

See all (24) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by SGD

Function Evidence Code Pubs
enables zinc ion binding RCA
inferred from Reviewed Computational Analysis
more info
 PubMed 
Process Evidence Code Pubs
involved_in RNA splicing IEA
Inferred from Electronic Annotation
more info
  
involved_in mRNA processing IEA
Inferred from Electronic Annotation
more info
  
involved_in mRNA splicing, via spliceosome IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in mRNA splicing, via spliceosome IEA
Inferred from Electronic Annotation
more info
  
involved_in mRNA splicing, via spliceosome IGI
Inferred from Genetic Interaction
more info
 PubMed 
involved_in mRNA splicing, via spliceosome IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in mRNA splicing, via spliceosome IPI
Inferred from Physical Interaction
more info
 PubMed 
involved_in response to xenobiotic stimulus IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in spliceosomal complex assembly IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in spliceosomal complex assembly IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
part_of U2 snRNP IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of U2 snRNP IDA
Inferred from Direct Assay
more info
 PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
  
part_of precatalytic spliceosome IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of spliceosomal complex IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
U2 snRNP complex subunit RDS3
NP_015419.1
  • Component of the SF3b subcomplex of the U2 snRNP; zinc cluster protein involved in pre-mRNA splicing and cycloheximide resistance

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001148.4 Reference assembly

    Range
    720637..720960
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001184191.1 → NP_015419.1  TPA: U2 snRNP complex subunit RDS3 [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_015419.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    D6W493, Q06835
    UniProtKB/TrEMBL
    A6ZWX6, B3LK60, C7GPT4, C8ZJB7, G2WPR2, N1NW34
    Conserved Domains (1) summary
    pfam03660
    Location:1 → 105
    PHF5; PHF5-like protein
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q06835.1

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