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INA17 Ina17p [ Saccharomyces cerevisiae S288C ]

Gene ID: 856005, updated on 2-Nov-2024

Summary

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Official Symbol
INA17
Official Full Name
Ina17p
Primary source
SGD:S000006020
Locus tag
YPL099C
See related
AllianceGenome:SGD:S000006020; FungiDB:YPL099C; VEuPathDB:YPL099C
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Also known as
AIM43; FMP14
Summary
Involved in mitochondrial proton-transporting ATP synthase complex assembly. Located in mitochondrial inner membrane. Part of INA complex. [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See INA17 in Genome Data Viewer
Location:
chromosome: XVI
Exon count:
1
Sequence:
Chromosome: XVI; NC_001148.4 (363520..364068, complement)

Chromosome XVI - NC_001148.4Genomic Context describing neighboring genes Neighboring gene Elongator subunit ELP4 Neighboring gene Atg21p Neighboring gene Mgr2p Neighboring gene tyrosine--tRNA ligase MSY1

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_001148.4

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. The INA complex facilitates assembly of the peripheral stalk of the mitochondrial F1Fo-ATP synthase. Lytovchenko O, et al. EMBO J, 2014 Aug 1. PMID 24942160, Free PMC Article
  2. Transfer of the Septin Ring to Cytokinetic Remnants in ER Stress Directs Age-Sensitive Cell-Cycle Re-entry. Chao JT, et al. Dev Cell, 2019 Oct 21. PMID 31564614, Free PMC Article
  3. A genomic analysis of chronological longevity factors in budding yeast. Burtner CR, et al. Cell Cycle, 2011 May 1. PMID 21447998, Free PMC Article
  4. INA complex liaises the F(1)F(o)-ATP synthase membrane motor modules. Naumenko N, et al. Nat Commun, 2017 Nov 1. PMID 29093463, Free PMC Article
  5. Molecular Connectivity of Mitochondrial Gene Expression and OXPHOS Biogenesis. Singh AP, et al. Mol Cell, 2020 Sep 17. PMID 32877643

See all (32) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. INAC maintains assembly intermediates of the F1 F0-ATP synthase in a primed state for the terminal assembly step-motor module formation.
    Title: INA complex liaises the F(1)F(o)-ATP synthase membrane motor modules.
  2. INA22 and INA17 complex facilitates assembly of the peripheral stalk of the mitochondrial F1Fo-ATP synthase.
    Title: The INA complex facilitates assembly of the peripheral stalk of the mitochondrial F1Fo-ATP synthase.
Submit: New GeneRIF Correction

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by SGD

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in mitochondrial proton-transporting ATP synthase complex assembly IGI
Inferred from Genetic Interaction
more info
 PubMed 
involved_in mitochondrial proton-transporting ATP synthase complex assembly IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
part_of INA complex IDA
Inferred from Direct Assay
more info
 PubMed 
part_of INA complex IPI
Inferred from Physical Interaction
more info
 PubMed 
located_in mitochondrial inner membrane IDA
Inferred from Direct Assay
more info
 PubMed 
located_in mitochondrial inner membrane IEA
Inferred from Electronic Annotation
more info
  
located_in mitochondrion HDA PubMed 
located_in mitochondrion IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
Ina17p
NP_015226.1
  • F1F0 ATPase synthase peripheral stalk assembly factor; subunit of the matrix-exposed inner mitochondrial membrane localized INA complex (Ina22p-Ina17p) involved in assembly of the F1F0 peripheral stalk; co-purifies with Ina22p and ATP synthase subunits; null mutant displays elevated frequency of mitochondrial genome loss and has a respiratory growth defect

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001148.4 Reference assembly

    Range
    363520..364068 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001183913.1 → NP_015226.1  TPA: Ina17p [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_015226.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    A6ZWF1, B3LKX3, B5VT63, C8ZIT1, D6W3R7, Q02888
    UniProtKB/TrEMBL
    N1NVW8
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q02888.1

Gene LinkOut

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