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ABZ1 4-amino-4-deoxychorismate synthase [ Saccharomyces cerevisiae S288C ]

Gene ID: 855768, updated on 14-Nov-2024

Summary

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Official Symbol
ABZ1
Official Full Name
4-amino-4-deoxychorismate synthase
Primary source
SGD:S000005316
Locus tag
YNR033W
See related
AllianceGenome:SGD:S000005316; FungiDB:YNR033W; VEuPathDB:YNR033W
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Summary
Enables 4-amino-4-deoxychorismate synthase activity. Involved in para-aminobenzoic acid biosynthetic process. Located in cytoplasm. [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See ABZ1 in Genome Data Viewer
Location:
chromosome: XIV
Exon count:
1
Sequence:
Chromosome: XIV; NC_001146.8 (687635..689998)

Chromosome XIV - NC_001146.8Genomic Context describing neighboring genes Neighboring gene putative serine/threonine-protein kinase PPG1 Neighboring gene ubiquitin-like protein HUB1 Neighboring gene Sol1p Neighboring gene Ego4p

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_001146.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Para-aminobenzoate synthase gene of Saccharomyces cerevisiae encodes a bifunctional enzyme. Edman JC, et al. Yeast, 1993 Jun. PMID 8346682
  2. Sulfa drug screening in yeast: fifteen sulfa drugs compete with p-aminobenzoate in Saccharomyces cerevisiae. Castelli LA, et al. FEMS Microbiol Lett, 2001 May 30. PMID 11377864
  3. para-Aminobenzoic acid is a precursor in coenzyme Q6 biosynthesis in Saccharomyces cerevisiae. Marbois B, et al. J Biol Chem, 2010 Sep 3. PMID 20592037, Free PMC Article
  4. QTL mapping of the production of wine aroma compounds by yeast. Steyer D, et al. BMC Genomics, 2012 Oct 30. PMID 23110365, Free PMC Article
  5. Production of aromatics in Saccharomyces cerevisiae--a feasibility study. Krömer JO, et al. J Biotechnol, 2013 Jan 20. PMID 22579724

See all (33) citations in PubMed

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by SGD

Function Evidence Code Pubs
enables 4-amino-4-deoxychorismate synthase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables 4-amino-4-deoxychorismate synthase activity IEA
Inferred from Electronic Annotation
more info
  
enables 4-amino-4-deoxychorismate synthase activity IMP
Inferred from Mutant Phenotype
more info
 PubMed 
enables 4-amino-4-deoxychorismate synthase activity ISS
Inferred from Sequence or Structural Similarity
more info
 PubMed 
enables transferase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in biosynthetic process IEA
Inferred from Electronic Annotation
more info
  
involved_in folic acid biosynthetic process IEA
Inferred from Electronic Annotation
more info
  
involved_in para-aminobenzoic acid biosynthetic process IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in para-aminobenzoic acid biosynthetic process IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in tetrahydrofolate biosynthetic process IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in cytoplasm HDA PubMed 
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
4-amino-4-deoxychorismate synthase
NP_014431.1
  • Para-aminobenzoate (PABA) synthase; has similarity to Escherichia coli PABA synthase components PabA and PabB; required for the synthesis of para-aminobenzoic acid, an important intermediate for folate and ubiquinone Q biosynthesis; protein abundance increases in response to DNA replication stress

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001146.8 Reference assembly

    Range
    687635..689998
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001183210.1 → NP_014431.1  TPA: 4-amino-4-deoxychorismate synthase [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_014431.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    D6W1K8, P37254, Q02982, Q6B1Q1
    UniProtKB/TrEMBL
    N1NWU0
    Conserved Domains (1) summary
    TIGR01823
    Location:10 → 787
    PabB-fungal; aminodeoxychorismate synthase, fungal clade
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P37254.4

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