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FMP41 Fmp41p [ Saccharomyces cerevisiae S288C ]

Gene ID: 855553, updated on 18-Sep-2024

Summary

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Official Symbol
FMP41
Official Full Name
Fmp41p
Primary source
SGD:S000005112
Locus tag
YNL168C
See related
AllianceGenome:SGD:S000005112; FungiDB:YNL168C; VEuPathDB:YNL168C
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Summary
Predicted to enable acetylpyruvate hydrolase activity. Located in mitochondrion. Orthologous to human FAHD1 (fumarylacetoacetate hydrolase domain containing 1). [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

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See FMP41 in Genome Data Viewer
Location:
chromosome: XIV
Exon count:
1
Sequence:
Chromosome: XIV; NC_001146.8 (318030..318809, complement)

Chromosome XIV - NC_001146.8Genomic Context describing neighboring genes Neighboring gene anaphase promoting complex subunit 1 Neighboring gene phosphatidylserine decarboxylase 1 Neighboring gene Sko1p Neighboring gene Bni5p

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_001146.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Disruption and basic phenotypic analysis of six novel genes from the left arm of chromosome XIV of Saccharomyces cerevisiae. Dueñas E, et al. Yeast, 1999 Jan 15. PMID 10028186
  2. Global protein expression profiling of budding yeast in response to DNA damage. Lee MW, et al. Yeast, 2007 Mar. PMID 17351896
  3. A genomic analysis of chronological longevity factors in budding yeast. Burtner CR, et al. Cell Cycle, 2011 May 1. PMID 21447998, Free PMC Article
  4. The nucleotide sequence of Saccharomyces cerevisiae chromosome XIV and its evolutionary implications. Philippsen P, et al. Nature, 1997 May 29. PMID 9169873
  5. The proteome of Saccharomyces cerevisiae mitochondria. Sickmann A, et al. Proc Natl Acad Sci U S A, 2003 Nov 11. PMID 14576278, Free PMC Article

See all (19) citations in PubMed

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by SGD

Function Evidence Code Pubs
enables acetylpyruvate hydrolase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables catalytic activity IEA
Inferred from Electronic Annotation
more info
  
enables isomerase activity IEA
Inferred from Electronic Annotation
more info
  
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
  
enables molecular_function ND
No biological Data available
more info
  
enables oxaloacetate tautomerase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
  
Component Evidence Code Pubs
located_in mitochondrion HDA PubMed 
is_active_in mitochondrion IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in mitochondrion IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
Fmp41p
NP_014231.1
  • hypothetical protein; GFP-fusion protein is induced in response to the DNA-damaging agent MMS; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001146.8 Reference assembly

    Range
    318030..318809 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001183006.1 → NP_014231.1  TPA: Fmp41p [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_014231.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    D6W114, P53889
    UniProtKB/TrEMBL
    A6ZRR5, B3LP22, B5VQN9, C7GTE5, C8ZG60, G2WLT8, N1NWG6
    Conserved Domains (1) summary
    COG0179
    Location:6 → 233
    MhpD; 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) [Secondary metabolites biosynthesis, transport and catabolism]
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P53889.1

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