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GSR1 Gsr1p [ Saccharomyces cerevisiae S288C ]

Gene ID: 855341, updated on 3-Nov-2024

Summary

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Official Symbol
GSR1
Official Full Name
Gsr1p
Primary source
SGD:S000004910
Locus tag
YMR295C
See related
AllianceGenome:SGD:S000004910; FungiDB:YMR295C; VEuPathDB:YMR295C
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Summary
Acts upstream of or within regulation of cell wall (1->3)-beta-D-glucan biosynthetic process. Located in several cellular components, including cellular bud neck; cellular bud tip; and mating projection tip. [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See GSR1 in Genome Data Viewer
Location:
chromosome: XIII
Exon count:
1
Sequence:
Chromosome: XIII; NC_001145.3 (858297..858890, complement)

Chromosome XIII - NC_001145.3Genomic Context describing neighboring genes Neighboring gene glutamyl-tRNA(Gln) amidotransferase subunit HER2 Neighboring gene Jnm1p Neighboring gene serine C-palmitoyltransferase LCB1 Neighboring gene carboxypeptidase C PRC1

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_001145.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Proteome-scale movements and compartment connectivity during the eukaryotic cell cycle. Litsios A, et al. Cell, 2024 Mar 14. PMID 38452761,
  2. Identification of Novel Components of Target-of-Rapamycin Signaling Pathway by Network-Based Multi-Omics Integrative Analysis. Dereli Eke E, et al. OMICS, 2019 May. PMID 30985253
  3. Identification of mitogen-activated protein kinase signaling pathways that confer resistance to endoplasmic reticulum stress in Saccharomyces cerevisiae. Chen Y, et al. Mol Cancer Res, 2005 Dec. PMID 16380504
  4. Nonsense-mediated mRNA decay involves two distinct Upf1-bound complexes. Dehecq M, et al. EMBO J, 2018 Nov 2. PMID 30275269, Free PMC Article
  5. Reverse recruitment: the Nup84 nuclear pore subcomplex mediates Rap1/Gcr1/Gcr2 transcriptional activation. Menon BB, et al. Proc Natl Acad Sci U S A, 2005 Apr 19. PMID 15817685, Free PMC Article

See all (40) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by SGD

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within regulation of cell wall (1->3)-beta-D-glucan biosynthetic process IGI
Inferred from Genetic Interaction
more info
 PubMed 
acts_upstream_of_or_within regulation of cell wall (1->3)-beta-D-glucan biosynthetic process IPI
Inferred from Physical Interaction
more info
 PubMed 
Component Evidence Code Pubs
located_in cell periphery HDA PubMed 
located_in cellular bud HDA PubMed 
located_in cellular bud neck HDA PubMed 
located_in cellular bud tip HDA PubMed 
located_in mating projection tip HDA PubMed 

General protein information

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Preferred Names
Gsr1p
NP_014024.1
  • Putative regulator of 1,3-beta-glucan biosynthesis; interacts with the catalytic (Fks1p and Gsc2p) and regulatory subunits (Rho1p) of 1,3-beta-glucan synthase; has a negative genetic interaction with RHO1; localizes to the cell periphery during early G1, to the bud tip in late G1, to the bud at S/G2, to the periphery of the bud at metaphase and at the bud neck during telophase; periodically expressed during the cell cycle; protein abundance increases in response to DNA replication stress

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001145.3 Reference assembly

    Range
    858297..858890 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001182804.1 → NP_014024.1  TPA: Gsr1p [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_014024.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    D6W0C2, Q03559
    UniProtKB/TrEMBL
    A6ZN11, B5VQ62, C7GTK4, C8ZFG4, G2WL04, N1P626
    Conserved Domains (1) summary
    pfam10295
    Location:49 → 116
    DUF2406; Uncharacterized protein (DUF2406)
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q03559.1

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