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ABZ2 aminodeoxychorismate lyase ABZ2 [ Saccharomyces cerevisiae S288C ]

Gene ID: 855333, updated on 2-Nov-2024

Summary

Official Symbol
ABZ2
Official Full Name
aminodeoxychorismate lyase ABZ2
Primary source
SGD:S000004902
Locus tag
YMR289W
See related
AllianceGenome:SGD:S000004902; FungiDB:YMR289W; VEuPathDB:YMR289W
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Summary
Enables 4-amino-4-deoxychorismate lyase activity. Involved in folic acid biosynthetic process. Located in cytoplasm. [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

See ABZ2 in Genome Data Viewer
Location:
chromosome: XIII
Exon count:
1
Sequence:
Chromosome: XIII; NC_001145.3 (848685..849809)

Chromosome XIII - NC_001145.3Genomic Context describing neighboring genes Neighboring gene exoribonuclease II Neighboring gene U2 snRNP complex subunit HSH155 Neighboring gene ATP-dependent RNA helicase HAS1 Neighboring gene protein kinase TDA1

Bibliography

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Gene Ontology Provided by SGD

Function Evidence Code Pubs
enables 4-amino-4-deoxychorismate lyase activity IDA
Inferred from Direct Assay
more info
PubMed 
enables 4-amino-4-deoxychorismate lyase activity IEA
Inferred from Electronic Annotation
more info
 
enables catalytic activity IEA
Inferred from Electronic Annotation
more info
 
enables lyase activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in carboxylic acid biosynthetic process IEA
Inferred from Electronic Annotation
more info
 
involved_in carboxylic acid metabolic process IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in folic acid biosynthetic process IEA
Inferred from Electronic Annotation
more info
 
involved_in folic acid biosynthetic process IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in tetrahydrofolate biosynthetic process IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
located_in cytoplasm HDA PubMed 
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
aminodeoxychorismate lyase ABZ2
NP_014016.1
  • Aminodeoxychorismate lyase (4-amino-4-deoxychorismate lyase); catalyzes the third step in para-aminobenzoic acid biosynthesis; involved in folic acid biosynthesis

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001145.3 Reference assembly

    Range
    848685..849809
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001182796.1NP_014016.1  TPA: aminodeoxychorismate lyase ABZ2 [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_014016.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    D6W0B6, Q03266, Q03531
    UniProtKB/TrEMBL
    A6ZN05, B3LMH7, C7GTL0, C8ZFF6, G2WKZ8, N1P0Q6
    Conserved Domains (1) summary
    COG0115
    Location:38366
    IlvE; Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase [Amino acid transport and metabolism, Coenzyme transport and metabolism]