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MTG1 putative GTPase MTG1 [ Saccharomyces cerevisiae S288C ]

Gene ID: 855122, updated on 2-Nov-2024

Summary

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Official Symbol
MTG1
Official Full Name
putative GTPase MTG1
Primary source
SGD:S000004703
Locus tag
YMR097C
See related
AllianceGenome:SGD:S000004703; FungiDB:YMR097C; VEuPathDB:YMR097C
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Summary
Predicted to enable GTPase activity. Involved in mitochondrial translation. Located in mitochondrial inner membrane. Orthologous to human MTG1 (mitochondrial ribosome associated GTPase 1). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See MTG1 in Genome Data Viewer
Location:
chromosome: XIII
Exon count:
1
Sequence:
Chromosome: XIII; NC_001145.3 (459424..460527, complement)

Chromosome XIII - NC_001145.3Genomic Context describing neighboring genes Neighboring gene putative pyridoxal 5'-phosphate synthase Neighboring gene pyridoxine biosynthesis protein SNZ1 Neighboring gene Atp25p Neighboring gene tRNA-Asp

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_001145.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. MTG1 codes for a conserved protein required for mitochondrial translation. Barrientos A, et al. Mol Biol Cell, 2003 Jun. PMID 12808030, Free PMC Article
  2. Pleiotropic effects of the yeast Sal1 and Aac2 carriers on mitochondrial function via an activity distinct from adenine nucleotide transport. Kucejova B, et al. Mol Genet Genomics, 2008 Jul. PMID 18431598, Free PMC Article
  3. The DEAD-box helicase Mss116 plays distinct roles in mitochondrial ribogenesis and mRNA-specific translation. De Silva D, et al. Nucleic Acids Res, 2017 Jun 20. PMID 28520979, Free PMC Article
  4. A role for the nucleoporin Nup170p in chromatin structure and gene silencing. Van de Vosse DW, et al. Cell, 2013 Feb 28. PMID 23452847, Free PMC Article
  5. Modeling complex genetic interactions in a simple eukaryotic genome: actin displays a rich spectrum of complex haploinsufficiencies. Haarer B, et al. Genes Dev, 2007 Jan 15. PMID 17167106, Free PMC Article

See all (28) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by SGD

Function Evidence Code Pubs
enables GTP binding IEA
Inferred from Electronic Annotation
more info
  
enables GTPase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables GTPase activity ISA
Inferred from Sequence Alignment
more info
 PubMed 
Process Evidence Code Pubs
involved_in mitochondrial translation IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in mitochondrial translation IGI
Inferred from Genetic Interaction
more info
 PubMed 
involved_in mitochondrial translation IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
located_in mitochondrial inner membrane IDA
Inferred from Direct Assay
more info
 PubMed 
located_in mitochondrial inner membrane IEA
Inferred from Electronic Annotation
more info
  
located_in mitochondrion HDA PubMed 
is_active_in mitochondrion IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in mitochondrion IEA
Inferred from Electronic Annotation
more info
  
located_in nucleus HDA PubMed 

General protein information

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Preferred Names
putative GTPase MTG1
NP_013815.1
  • Putative GTPase peripheral to the mitochondrial inner membrane; essential for respiratory competence, likely functions in assembly of the large ribosomal subunit, has homologs in plants and animals

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001145.3 Reference assembly

    Range
    459424..460527 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001182597.1 → NP_013815.1  TPA: putative GTPase MTG1 [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_013815.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    D6VZS0, Q03151
    UniProtKB/TrEMBL
    C7GL29, C8ZEU9, G2WKE5, N1NYC4
    Conserved Domains (1) summary
    COG1161
    Location:18 → 367
    RbgA; Ribosome biogenesis GTPase A [Translation, ribosomal structure and biogenesis]
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q03151.1

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