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MRPL39 mitochondrial 54S ribosomal protein YmL39 [ Saccharomyces cerevisiae S288C ]

Gene ID: 855002, updated on 14-Nov-2024

Summary

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Official Symbol
MRPL39
Official Full Name
mitochondrial 54S ribosomal protein YmL39
Primary source
SGD:S000004468
Locus tag
YML009C
See related
AllianceGenome:SGD:S000004468; FungiDB:YML009C; VEuPathDB:YML009C
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Also known as
bL33m
Summary
A structural constituent of ribosome. Predicted to be involved in mitochondrial translation. Located in mitochondrion. Part of mitochondrial large ribosomal subunit. Orthologous to human MRPL33 (mitochondrial ribosomal protein L33). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See MRPL39 in Genome Data Viewer
Location:
chromosome: XIII
Exon count:
1
Sequence:
Chromosome: XIII; NC_001145.3 (251304..251516, complement)

Chromosome XIII - NC_001145.3Genomic Context describing neighboring genes Neighboring gene Rad33p Neighboring gene transcription elongation factor SPT5 Neighboring gene sterol 24-C-methyltransferase Neighboring gene Min4p

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_001145.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Ribosome-binding proteins Mdm38 and Mba1 display overlapping functions for regulation of mitochondrial translation. Bauerschmitt H, et al. Mol Biol Cell, 2010 Jun 15. PMID 20427570, Free PMC Article
  2. Ribosomal protein L33 is required for ribosome biogenesis, subunit joining, and repression of GCN4 translation. Martín-Marcos P, et al. Mol Cell Biol, 2007 Sep. PMID 17548477, Free PMC Article
  3. Mdm38 is a 14-3-3-like receptor and associates with the protein synthesis machinery at the inner mitochondrial membrane. Lupo D, et al. Traffic, 2011 Oct. PMID 21718401
  4. Extended N-terminal sequencing of proteins of the large ribosomal subunit from yeast mitochondria. Grohmann L, et al. FEBS Lett, 1991 Jun 17. PMID 2060626
  5. Inhibition of RNA lariat debranching enzyme suppresses TDP-43 toxicity in ALS disease models. Armakola M, et al. Nat Genet, 2012 Dec. PMID 23104007, Free PMC Article

See all (37) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Results suggest that ribosomal protein L33 is required for ribosome biogenesis, subunit joining, and repression of GCN4 translation.
    Title: Ribosomal protein L33 is required for ribosome biogenesis, subunit joining, and repression of GCN4 translation.
Submit: New GeneRIF Correction

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by SGD

Function Evidence Code Pubs
enables structural constituent of ribosome IDA
Inferred from Direct Assay
more info
 PubMed 
enables structural constituent of ribosome IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in mitochondrial translation IC
Inferred by Curator
more info
 PubMed 
involved_in translation IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  
part_of mitochondrial large ribosomal subunit IDA
Inferred from Direct Assay
more info
 PubMed 
located_in mitochondrion HDA PubMed 
is_active_in mitochondrion IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in mitochondrion IEA
Inferred from Electronic Annotation
more info
  
part_of ribonucleoprotein complex IEA
Inferred from Electronic Annotation
more info
  
part_of ribosomal subunit IEA
Inferred from Electronic Annotation
more info
  
located_in ribosome IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
mitochondrial 54S ribosomal protein YmL39
NP_013705.1
  • Mitochondrial ribosomal protein of the large subunit

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001145.3 Reference assembly

    Range
    251304..251516 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001182364.1 → NP_013705.1  TPA: mitochondrial 54S ribosomal protein YmL39 [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_013705.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    D6VZG5, P36533
    UniProtKB/TrEMBL
    A6ZM53, B3LLP2, C7GLC7, C8ZEJ8, G2WK43, N1NX44
    Conserved Domains (1) summary
    cl00383
    Location:10 → 53
    Ribosomal_L33; Ribosomal protein L33
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P36533.3

Gene LinkOut

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