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MSC1 Msc1p [ Saccharomyces cerevisiae S288C ]

Gene ID: 854911, updated on 2-Nov-2024

Summary

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Official Symbol
MSC1
Official Full Name
Msc1p
Primary source
SGD:S000004597
Locus tag
YML128C
See related
AllianceGenome:SGD:S000004597; FungiDB:YML128C; VEuPathDB:YML128C
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Summary
Involved in reciprocal meiotic recombination. Located in mitochondrion. [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See MSC1 in Genome Data Viewer
Location:
chromosome: XIII
Exon count:
1
Sequence:
Chromosome: XIII; NC_001145.3 (15135..16676, complement)

Chromosome XIII - NC_001145.3Genomic Context describing neighboring genes Neighboring gene ER oxidoreductin Neighboring gene Cox14p Neighboring gene Rsc9p Neighboring gene hydroxymethylglutaryl-CoA synthase

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_001145.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Msc1 is a nuclear envelope protein that reinforces DNA repair in late mitosis. Medina-Suárez S, et al. iScience, 2024 Jul 19. PMID 39021806, Free PMC Article
  2. Stress response and expression patterns in wine fermentations of yeast genes induced at the diauxic shift. Puig S, et al. Yeast, 2000 Jan 30. PMID 10641036
  3. Genetic control of recombination partner preference in yeast meiosis. Isolation and characterization of mutants elevated for meiotic unequal sister-chromatid recombination. Thompson DA, et al. Genetics, 1999 Oct. PMID 10511544, Free PMC Article
  4. Yeast mitochondrial dehydrogenases are associated in a supramolecular complex. Grandier-Vazeille X, et al. Biochemistry, 2001 Aug 21. PMID 11502169
  5. Hsp104 disaggregase at normal levels cures many [PSI(+)] prion variants in a process promoted by Sti1p, Hsp90, and Sis1p. Gorkovskiy A, et al. Proc Natl Acad Sci U S A, 2017 May 23. PMID 28484020, Free PMC Article

See all (58) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by SGD

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in reciprocal meiotic recombination IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
located_in endoplasmic reticulum HDA PubMed 
located_in mitochondrion HDA PubMed 
located_in mitochondrion IDA
Inferred from Direct Assay
more info
 PubMed 
located_in plasma membrane HDA PubMed 

General protein information

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Preferred Names
Msc1p
NP_013578.1
  • hypothetical protein; mutant is defective in directing meiotic recombination events to homologous chromatids; the authentic, non-tagged protein is detected in highly purified mitochondria and is phosphorylated

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001145.3 Reference assembly

    Range
    15135..16676 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001182491.1 → NP_013578.1  TPA: Msc1p [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_013578.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    D6W0F7, Q03104
    UniProtKB/TrEMBL
    B3LLD2, C8ZE74, N1NXS7
    Conserved Domains (1) summary
    pfam10281
    Location:109 → 145
    Ish1; Putative stress-responsive nuclear envelope protein
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q03104.1

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