DAL3 ureidoglycolate hydrolase [Saccharomyces cerevisiae S288C] - Gene

Summary

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Official Symbol: DAL3
Official Full Name: ureidoglycolate hydrolase
Primary source: SGD:S000001471
Locus tag: YIR032C
See related: AllianceGenome:SGD:S000001471; FungiDB:YIR032C; VEuPathDB:YIR032C
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Saccharomyces cerevisiae S288C (strain: S288C)
Lineage: Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Summary: Enables ureidoglycolate lyase activity. Predicted to be involved in allantoin catabolic process. Predicted to be located in membrane. [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See DAL3 in Genome Data Viewer

Location:: chromosome: IX

Exon count:: 1

Sequence:: Chromosome: IX; NC_001141.2 (415030..415617, complement)

Chromosome IX - NC_001141.2 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_001141.2

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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Pathways from PubChem

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Homology

Orthologs from OrthoDB

Gene Ontology Provided by SGD

Function	Evidence Code	Pubs
enables lyase activity	IEA Inferred from Electronic Annotation more info
enables ureidoglycolate hydrolase activity	IEA Inferred from Electronic Annotation more info
enables ureidoglycolate lyase activity	IBA Inferred from Biological aspect of Ancestor more info
enables ureidoglycolate lyase activity	IDA Inferred from Direct Assay more info	PubMed
enables ureidoglycolate lyase activity	IEA Inferred from Electronic Annotation more info
enables ureidoglycolate lyase activity	IMP Inferred from Mutant Phenotype more info	PubMed

Process	Evidence Code	Pubs
involved_in allantoin catabolic process	IC Inferred by Curator more info	PubMed
involved_in allantoin catabolic process	IEA Inferred from Electronic Annotation more info
involved_in purine nucleobase metabolic process	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in membrane	ISS Inferred from Sequence or Structural Similarity more info	PubMed

General protein information

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Preferred Names: ureidoglycolate hydrolase

NP_012298.1

EC 4.3.2.3

Ureidoglycolate lyase; converts ureidoglycolate to glyoxylate and urea in the third step of allantoin degradation; expression is sensitive to nitrogen catabolite repression; this enzyme is sometimes referred to 'ureidoglycolate hydrolase' but should not be confused with the Arabidopsis thaliana ureidoglycolate hydrolase enzyme which converts ureidoglycolate to glyoxylate, ammonia and carbon dioxide

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

NC_001141.2 Reference assembly

Range

415030..415617 complement

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NM_001179554.1 → NP_012298.1 TPA: ureidoglycolate hydrolase [Saccharomyces cerevisiae S288C]

See identical proteins and their annotated locations for NP_012298.1

Status: REVIEWED

UniProtKB/Swiss-Prot

D6VVW3, P32459

UniProtKB/TrEMBL

C7GLS4, G2WFW0, N1P2C3

Conserved Domains (1) summary

COG3194
Location:1 → 195

AllA; Ureidoglycolate hydrolase (allantoin degradation) [Nucleotide transport and metabolism]