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INA22 Ina22p [ Saccharomyces cerevisiae S288C ]

Gene ID: 854842, updated on 2-Nov-2024

Summary

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Official Symbol
INA22
Official Full Name
Ina22p
Primary source
SGD:S000001463
Locus tag
YIR024C
See related
AllianceGenome:SGD:S000001463; FungiDB:YIR024C; VEuPathDB:YIR024C
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Summary
Involved in mitochondrial proton-transporting ATP synthase complex assembly. Located in mitochondrial inner membrane. Part of INA complex. [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See INA22 in Genome Data Viewer
Location:
chromosome: IX
Exon count:
1
Sequence:
Chromosome: IX; NC_001141.2 (402841..403491, complement)

Chromosome IX - NC_001141.2Genomic Context describing neighboring genes Neighboring gene signal peptidase complex catalytic subunit SEC11 Neighboring gene Dal81p Neighboring gene Mnd2p Neighboring gene tyrosine protein phosphatase YVH1

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_001141.2

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. The INA complex facilitates assembly of the peripheral stalk of the mitochondrial F1Fo-ATP synthase. Lytovchenko O, et al. EMBO J, 2014 Aug 1. PMID 24942160, Free PMC Article
  2. Systematic screen for human disease genes in yeast. Steinmetz LM, et al. Nat Genet, 2002 Aug. PMID 12134146
  3. Identification of aluminium transport-related genes via genome-wide phenotypic screening of Saccharomyces cerevisiae. Tun NM, et al. Metallomics, 2014 Aug. PMID 24926745
  4. Genetic basis for Saccharomyces cerevisiae biofilm in liquid medium. Scherz K, et al. G3 (Bethesda), 2014 Jul 9. PMID 25009170, Free PMC Article
  5. Heme, A Metabolic Sensor, Directly Regulates the Activity of the KDM4 Histone Demethylase Family and Their Interactions with Partner Proteins. Konduri PC, et al. Cells, 2020 Mar 22. PMID 32235736, Free PMC Article

See all (29) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. INAC maintains assembly intermediates of the F1 F0-ATP synthase in a primed state for the terminal assembly step-motor module formation.
    Title: INA complex liaises the F(1)F(o)-ATP synthase membrane motor modules.
  2. INA22 and INA17 complex facilitates assembly of the peripheral stalk of the mitochondrial F1Fo-ATP synthase.
    Title: The INA complex facilitates assembly of the peripheral stalk of the mitochondrial F1Fo-ATP synthase.
Submit: New GeneRIF Correction

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by SGD

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in mitochondrial proton-transporting ATP synthase complex assembly IGI
Inferred from Genetic Interaction
more info
 PubMed 
involved_in mitochondrial proton-transporting ATP synthase complex assembly IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
part_of INA complex IDA
Inferred from Direct Assay
more info
 PubMed 
part_of INA complex IPI
Inferred from Physical Interaction
more info
 PubMed 
located_in mitochondrial inner membrane IDA
Inferred from Direct Assay
more info
 PubMed 
located_in mitochondrial inner membrane IEA
Inferred from Electronic Annotation
more info
  
located_in mitochondrion HDA PubMed 
located_in mitochondrion IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
Ina22p
NP_012290.1
  • F1F0 ATP synthase peripheral stalk assembly factor; subunit of the matrix-exposed inner mitochondrial membrane localized INA complex (Ina22p-Ina17p) involved in assembly of the F1F0 peripheral stalk; co-purifies with Aim43p, ATP synthase subunits, and cytochrome bc1 complex assembly factors; interacts with Arh1p, a mitochondrial oxidoreductase; deletion mutant has a respiratory growth defect

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001141.2 Reference assembly

    Range
    402841..403491 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001179546.1 → NP_012290.1  TPA: Ina22p [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_012290.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    D6VVV5, P40576
    UniProtKB/TrEMBL
    B3LTI5, C7GLT2, N1P4A1
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P40576.1

Gene LinkOut

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