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SGN1 Sgn1p [ Saccharomyces cerevisiae S288C ]

Gene ID: 854817, updated on 2-Nov-2024

Summary

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Official Symbol
SGN1
Official Full Name
Sgn1p
Primary source
SGD:S000001440
Locus tag
YIR001C
See related
AllianceGenome:SGD:S000001440; FungiDB:YIR001C; VEuPathDB:YIR001C
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Also known as
RBP1; RBP29
Summary
Enables poly(A) binding activity. Involved in mRNA metabolic process. Located in cytoplasm. Human ortholog(s) of this gene implicated in oculopharyngeal muscular dystrophy. Orthologous to human PABPN1L (PABPN1 like, cytoplasmic) and PABPN1 (poly(A) binding protein nuclear 1). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See SGN1 in Genome Data Viewer
Location:
chromosome: IX
Exon count:
1
Sequence:
Chromosome: IX; NC_001141.2 (356143..356895, complement)

Chromosome IX - NC_001141.2Genomic Context describing neighboring genes Neighboring gene phosphoinositide 5-phosphatase INP51 Neighboring gene uncharacterized protein Neighboring gene 3'-5' DNA helicase Neighboring gene Aim21p

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_001141.2

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Rie1 and Sgn1 form an RNA-binding complex that enforces the meiotic entry cell fate decision.
    Title: Rie1 and Sgn1 form an RNA-binding complex that enforces the meiotic entry cell fate decision.
Submit: New GeneRIF Correction

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by SGD

Function Evidence Code Pubs
enables RNA binding IEA
Inferred from Electronic Annotation
more info
  
enables poly(A) binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables poly(A) binding IDA
Inferred from Direct Assay
more info
 PubMed 
Process Evidence Code Pubs
involved_in mRNA metabolic process IGI
Inferred from Genetic Interaction
more info
 PubMed 
involved_in mRNA metabolic process IPI
Inferred from Physical Interaction
more info
 PubMed 
Component Evidence Code Pubs
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in cytoplasm IDA
Inferred from Direct Assay
more info
 PubMed 
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
Sgn1p
NP_012266.1
  • Cytoplasmic RNA-binding protein; contains an RNA recognition motif (RRM); may have a role in mRNA translation, as suggested by genetic interactions with genes encoding proteins involved in translational initiation

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001141.2 Reference assembly

    Range
    356143..356895 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001179523.1 → NP_012266.1  TPA: Sgn1p [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_012266.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    D6VVT1, P40561
    UniProtKB/TrEMBL
    A6ZVR9, B3LTK8, C7GJH1, C8ZAQ0, G2WGE7, N1P0Q0
    Conserved Domains (2) summary
    COG0724
    Location:16 → 248
    RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
    cd12306
    Location:65 → 137
    RRM_II_PABPs; RNA recognition motif in type II polyadenylate-binding proteins
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P40561.1

Gene LinkOut

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