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TED1 Ted1p [ Saccharomyces cerevisiae S288C ]

Gene ID: 854772, updated on 2-Nov-2024

Summary

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Official Symbol
TED1
Official Full Name
Ted1p
Primary source
SGD:S000001301
Locus tag
YIL039W
See related
AllianceGenome:SGD:S000001301; FungiDB:YIL039W; VEuPathDB:YIL039W
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Summary
Predicted to enable hydrolase activity. Involved in endoplasmic reticulum to Golgi vesicle-mediated transport. Located in endoplasmic reticulum. [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See TED1 in Genome Data Viewer
Location:
chromosome: IX
Exon count:
1
Sequence:
Chromosome: IX; NC_001141.2 (278426..279847)

Chromosome IX - NC_001141.2Genomic Context describing neighboring genes Neighboring gene Gvp36p Neighboring gene Apq12p Neighboring gene CCR4-NOT core subunit NOT3 Neighboring gene pheromone-regulated protein PRM2

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_001141.2

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. COPII coat composition is actively regulated by luminal cargo maturation. Manzano-Lopez J, et al. Curr Biol, 2015 Jan 19. PMID 25557665
  2. PMT1 deficiency extends the shortened replicative lifespan of TED1-deficient yeast in a Hac1p-dependent manner. Cui HJ, et al. FEMS Microbiol Lett, 2018 Nov 1. PMID 30265296
  3. Lipid moiety of glycosylphosphatidylinositol-anchored proteins contributes to the determination of their final destination in yeast. Yoko-O T, et al. Genes Cells, 2018 Oct. PMID 30133879
  4. Mechanism of selectivity of an angiogenesis inhibitor from screening a genome-wide set of Saccharomyces cerevisiae deletion strains. Dilda PJ, et al. J Natl Cancer Inst, 2005 Oct 19. PMID 16234568
  5. Identification of yeast proteins necessary for cell-surface function of a potassium channel. Haass FA, et al. Proc Natl Acad Sci U S A, 2007 Nov 13. PMID 17989219, Free PMC Article

See all (46) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by SGD

Function Evidence Code Pubs
enables hydrolase activity IEA
Inferred from Electronic Annotation
more info
  
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in GPI anchor biosynthetic process IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in GPI anchor biosynthetic process IEA
Inferred from Electronic Annotation
more info
  
involved_in endoplasmic reticulum to Golgi vesicle-mediated transport IGI
Inferred from Genetic Interaction
more info
 PubMed 
involved_in endoplasmic reticulum to Golgi vesicle-mediated transport IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
located_in endoplasmic reticulum HDA PubMed 
is_active_in endoplasmic reticulum IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in endoplasmic reticulum IEA
Inferred from Electronic Annotation
more info
  
located_in endoplasmic reticulum membrane IEA
Inferred from Electronic Annotation
more info
  
located_in membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
Ted1p
NP_012225.1
  • GPI-glycan remodelase; conserved phosphoesterase domain-containing protein; acts together with Emp24p/Erv25p in cargo exit from the ER; functional ortholog of mammalian GPI-glycan remodelase PGAP5; deletion confers sensitivity to 4-(N-(S-glutathionylacetyl)amino) phenylarsenoxide (GSAO)

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001141.2 Reference assembly

    Range
    278426..279847
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001179389.1 → NP_012225.1  TPA: Ted1p [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_012225.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    D6VVP3, P40533
    UniProtKB/TrEMBL
    A6ZVN0, B3LTP5, B5VKQ7, C7GVW7, C8ZAK7, G2WGA7, N1P266
    Conserved Domains (1) summary
    cd08164
    Location:83 → 421
    MPP_Ted1; Saccharomyces cerevisiae Ted1 and related proteins, metallophosphatase domain
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P40533.1

Gene LinkOut

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