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RPL16A ribosomal 60S subunit protein L16A [ Saccharomyces cerevisiae S288C ]

Gene ID: 854673, updated on 7-Jul-2024

Summary

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Gene symbol
RPL16A
Gene description
ribosomal 60S subunit protein L16A
Primary source
FungiDB:YIL133C
Locus tag
YIL133C
See related
SGD:S000001395; AllianceGenome:SGD:S000001395; VEuPathDB:YIL133C
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Also known as
RPL13
Summary
Enables RNA binding activity. Involved in maturation of LSU-rRNA. Part of cytosolic large ribosomal subunit. Is active in nucleolus. Orthologous to human RPL13A (ribosomal protein L13a). [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

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See RPL16A in Genome Data Viewer
Location:
chromosome: IX
Exon count:
2
Sequence:
Chromosome: IX; NC_001141.2 (98527..99416, complement)

Chromosome IX - NC_001141.2Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene flavin adenine dinucleotide transporter FLX1 Neighboring gene Csm2p Neighboring gene forkhead family transcription factor FKH1

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_001141.2

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Role of the yeast ribosomal protein L16 in ribosome biogenesis. Espinar-Marchena FJ, et al. FEBS J, 2016 Aug. PMID 27374275
  2. Ribosomal protein L14 contributes to the early assembly of 60S ribosomal subunits in Saccharomyces cerevisiae. Espinar-Marchena F, et al. Nucleic Acids Res, 2018 May 18. PMID 29788267, Free PMC Article
  3. Vanillin inhibits translation and induces messenger ribonucleoprotein (mRNP) granule formation in saccharomyces cerevisiae: application and validation of high-content, image-based profiling. Iwaki A, et al. PLoS One, 2013. PMID 23637899, Free PMC Article
  4. Affinity purification of ribosomes to access the translatome. Halbeisen RE, et al. Methods, 2009 Jul. PMID 19398006
  5. Association of RAP1 binding sites with stringent control of ribosomal protein gene transcription in Saccharomyces cerevisiae. Moehle CM, et al. Mol Cell Biol, 1991 May. PMID 2017175, Free PMC Article

See all (125) citations in PubMed

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by SGD

Function Evidence Code Pubs
enables RNA binding IDA
Inferred from Direct Assay
more info
 PubMed 
enables mRNA binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables structural constituent of ribosome IBA
Inferred from Biological aspect of Ancestor
more info
  
enables structural constituent of ribosome IC
Inferred by Curator
more info
 PubMed 
enables structural constituent of ribosome IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in cytoplasmic translation IC
Inferred by Curator
more info
 PubMed 
involved_in maturation of LSU-rRNA IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in negative regulation of translation IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in translation IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  
part_of cytosolic large ribosomal subunit IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of cytosolic large ribosomal subunit IDA
Inferred from Direct Assay
more info
 PubMed 
part_of large ribosomal subunit IEA
Inferred from Electronic Annotation
more info
  
is_active_in nucleolus IDA
Inferred from Direct Assay
more info
 PubMed 
part_of ribonucleoprotein complex IEA
Inferred from Electronic Annotation
more info
  
is_active_in ribosome IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in ribosome IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
ribosomal 60S subunit protein L16A
NP_012133.1
  • Ribosomal 60S subunit protein L16A; N-terminally acetylated, binds 5.8 S rRNA; transcriptionally regulated by Rap1p; homologous to mammalian ribosomal protein L13A and bacterial L13; RPL16A has a paralog, RPL16B, that arose from the whole genome duplication; protein abundance increases in response to DNA replication stress

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001141.2 Reference assembly

    Range
    98527..99416 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001179481.1 → NP_012133.1  TPA: ribosomal 60S subunit protein L16A [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_012133.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    D6VVF4, P26784
    UniProtKB/TrEMBL
    A6ZVE3, B3LTY0, C8ZAY1, G2WG18, N1P0T6
    Conserved Domains (1) summary
    PTZ00068
    Location:6 → 199
    PTZ00068; 60S ribosomal protein L13a; Provisional
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P26784.3

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