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ERR1 [ Saccharomyces cerevisiae S288C ]

Gene ID: 854575, updated on 11-Sep-2024

Summary

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Official Symbol
ERR1
Primary source
SGD:S000005920
Locus tag
YOR393W
See related
AllianceGenome:SGD:S000005920; FungiDB:YOR393W; VEuPathDB:YOR393W
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Summary
Predicted to enable phosphopyruvate hydratase activity. Predicted to be involved in glycolytic process. Predicted to be part of phosphopyruvate hydratase complex. Human ortholog(s) of this gene implicated in Alzheimer's disease and prostate cancer. Orthologous to human ENO1 (enolase 1); ENO2 (enolase 2); and ENO3 (enolase 3). [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

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Location:
chromosome: XV
Exon count:
1
Sequence:
Chromosome: XV; NC_001147.6 (1080276..1081589)

Chromosome XV - NC_001147.6Genomic Context describing neighboring genes Neighboring gene fluoride transporter Neighboring gene glutathione-independent methylglyoxalase family protein Neighboring gene seripauperin PAU21 Neighboring gene uncharacterized protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_001147.6

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Sequence analysis of the right end of chromosome XV in Saccharomyces cerevisiae: an insight into the structural and functional significance of sub-telomeric repeat sequences. Pryde FE, et al. Yeast, 1995 Apr 15. PMID 7785338
  2. Multiple knockout analysis of genetic robustness in the yeast metabolic network. Deutscher D, et al. Nat Genet, 2006 Sep. PMID 16941010
  3. The nucleotide sequence of Saccharomyces cerevisiae chromosome XV. Dujon B, et al. Nature, 1997 May 29. PMID 9169874
  4. An integrated approach to characterize genetic interaction networks in yeast metabolism. Szappanos B, et al. Nat Genet, 2011 May 29. PMID 21623372, Free PMC Article
  5. Global analysis of genetic circuitry and adaptive mechanisms enabling resistance to the azole antifungal drugs. Mount HO, et al. PLoS Genet, 2018 Apr. PMID 29702647, Free PMC Article

See all (12) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by SGD

Function Evidence Code Pubs
enables lyase activity IEA
Inferred from Electronic Annotation
more info
  
enables magnesium ion binding IEA
Inferred from Electronic Annotation
more info
  
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
  
enables phosphopyruvate hydratase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables phosphopyruvate hydratase activity IEA
Inferred from Electronic Annotation
more info
  
enables phosphopyruvate hydratase activity ISA
Inferred from Sequence Alignment
more info
 PubMed 
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
  
involved_in glycolytic process IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in glycolytic process IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
is_active_in cellular_component ND
No biological Data available
more info
  
part_of phosphopyruvate hydratase complex IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of phosphopyruvate hydratase complex IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
phosphopyruvate hydratase ERR1
NP_015038.1
  • Putative phosphopyruvate hydratase

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001147.6 Reference assembly

    Range
    1080276..1081589
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001183813.1 → NP_015038.1  TPA: phosphopyruvate hydratase ERR1 [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_015038.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    D6W385, P0CX10, P0CX11, Q12007, Q7LGJ4
    UniProtKB/TrEMBL
    A6ZVX7, B3LK45, B5VSR2, C7GSW8, C8ZHE0
    Conserved Domains (1) summary
    PTZ00081
    Location:1 → 428
    PTZ00081; enolase; Provisional
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P0CX10.1
P0CX11.1

Gene LinkOut

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