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TFB6 TFIIH complex subunit TFB6 [ Saccharomyces cerevisiae S288C ]

Gene ID: 854534, updated on 18-Sep-2024

Summary

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Official Symbol
TFB6
Official Full Name
TFIIH complex subunit TFB6
Primary source
SGD:S000005879
Locus tag
YOR352W
See related
AllianceGenome:SGD:S000005879; FungiDB:YOR352W; VEuPathDB:YOR352W
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Summary
Located in cytoplasm and nucleus. Part of transcription factor TFIIH holo complex. [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

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See TFB6 in Genome Data Viewer
Location:
chromosome: XV
Exon count:
1
Sequence:
Chromosome: XV; NC_001147.6 (997213..998244)

Chromosome XV - NC_001147.6Genomic Context describing neighboring genes Neighboring gene Mne1p Neighboring gene serine/threonine protein kinase MEK1 Neighboring gene Sog2p Neighboring gene Msc6p

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_001147.6

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Regulation of gene expression by a metabolic enzyme. Hall DA, et al. Science, 2004 Oct 15. PMID 15486299
  2. Function of Conserved Topological Regions within the Saccharomyces cerevisiae Basal Transcription Factor TFIIH. Warfield L, et al. Mol Cell Biol, 2016 Oct 1. PMID 27381459, Free PMC Article
  3. Tfb6, a previously unidentified subunit of the general transcription factor TFIIH, facilitates dissociation of Ssl2 helicase after transcription initiation. Murakami K, et al. Proc Natl Acad Sci U S A, 2012 Mar 27. PMID 22411836, Free PMC Article
  4. Structure of an RNA polymerase II preinitiation complex. Murakami K, et al. Proc Natl Acad Sci U S A, 2015 Nov 3. PMID 26483468, Free PMC Article
  5. Architecture of an RNA polymerase II transcription pre-initiation complex. Murakami K, et al. Science, 2013 Nov 8. PMID 24072820, Free PMC Article

See all (26) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by SGD

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
  
Component Evidence Code Pubs
located_in cytoplasm HDA PubMed 
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  
located_in nucleus HDA PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
  
part_of transcription factor TFIIH holo complex IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of transcription factor TFIIH holo complex IDA
Inferred from Direct Assay
more info
 PubMed 

General protein information

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Preferred Names
TFIIH complex subunit TFB6
NP_014997.1
  • Subunit of TFIIH complex; facilities dissociation of the Ssl2p helices from TFIIH; expression levels regulated by Arg5,6p; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm and nucleus

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001147.6 Reference assembly

    Range
    997213..998244
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001183772.1 → NP_014997.1  TPA: TFIIH complex subunit TFB6 [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_014997.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    D6W347, Q08816
    UniProtKB/TrEMBL
    A6ZPI2, B3LK09, C7GNR6, C8ZHA3, G2WNL3, N1P3V7
    Conserved Domains (1) summary
    pfam17110
    Location:164 → 334
    TFB6; Subunit 11 of the general transcription factor TFIIH
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q08816.1

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