RIM20 Rim20p [Saccharomyces cerevisiae S288C] - Gene

Summary

Official Symbol: RIM20
Official Full Name: Rim20p
Primary source: SGD:S000005801
Locus tag: YOR275C
See related: AllianceGenome:SGD:S000005801; FungiDB:YOR275C; VEuPathDB:YOR275C
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Saccharomyces cerevisiae S288C (strain: S288C)
Lineage: Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Summary: Involved in invasive growth in response to glucose limitation; protein processing; and sporulation resulting in formation of a cellular spore. Located in peroxisome. Human ortholog(s) of this gene implicated in primary autosomal recessive microcephaly. Orthologous to human PDCD6IP (programmed cell death 6 interacting protein). [provided by Alliance of Genome Resources, Nov 2024]
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Chromosome XV - NC_001147.6 Genomic Context describing neighboring genes

Go to nucleotide: Graphics FASTA GenBank

Lithium chloride sensitivity connects the activity of PEX11 and RIM20 to the translation of PGM2 and other mRNAs with structured 5'-UTRs.
Title: Lithium chloride sensitivity connects the activity of PEX11 and RIM20 to the translation of PGM2 and other mRNAs with structured 5'-UTRs.
Results show that the pH-dependent localization of Rim20 is contingent on the amount of Bro1 in the cell.
Title: Intervention of Bro1 in pH-responsive Rim20 localization in Saccharomyces cerevisiae.
Alkaline growth conditions alter the endosomal surface to favor Rim20-Snf7 interaction and Rim101 cleavage.
Title: Control of Bro1-domain protein Rim20 localization by external pH, ESCRT machinery, and the Saccharomyces cerevisiae Rim101 pathway.

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

Function	Evidence Code	Pubs
enables molecular_function	ND No biological Data available more info

Process	Evidence Code	Pubs
involved_in invasive growth in response to glucose limitation	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in multivesicular body sorting pathway	IEA Inferred from Electronic Annotation more info
involved_in protein processing	IDA Inferred from Direct Assay more info	PubMed
involved_in protein processing	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in sporulation resulting in formation of a cellular spore	IMP Inferred from Mutant Phenotype more info	PubMed

Component	Evidence Code	Pubs
located_in cytoplasm	HDA more info	PubMed
located_in cytoplasm	IEA Inferred from Electronic Annotation more info
is_active_in endosome	IBA Inferred from Biological aspect of Ancestor more info
located_in nucleus	HDA more info	PubMed
located_in nucleus	IEA Inferred from Electronic Annotation more info
located_in peroxisome	IDA Inferred from Direct Assay more info	PubMed

NP_014918.1

Protein involved in proteolytic activation of Rim101p; part of response to alkaline pH; PalA/AIP1/Alix family member; interaction with the ESCRT-III subunit Snf7p suggests a relationship between pH response and multivesicular body formation; localizes to cytosol, nucleus and peroxisomes

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The following sections contain reference sequences that belong to a specific genome build. Explain