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RPS7A ribosomal 40S subunit protein S7A [ Saccharomyces cerevisiae S288C ]

Gene ID: 854263, updated on 2-Nov-2024

Summary

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Official Symbol
RPS7A
Official Full Name
ribosomal 40S subunit protein S7A
Primary source
SGD:S000005622
Locus tag
YOR096W
See related
AllianceGenome:SGD:S000005622; FungiDB:YOR096W; VEuPathDB:YOR096W
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Also known as
RPS30
Summary
Predicted to be a structural constituent of ribosome. Involved in ribosome biogenesis. Part of small-subunit processome. Human ortholog(s) of this gene implicated in Diamond-Blackfan anemia 8. Orthologous to human RPS7 (ribosomal protein S7). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See RPS7A in Genome Data Viewer
Location:
chromosome: XV
Exon count:
2
Sequence:
Chromosome: XV; NC_001147.6 (505794..506767)

Chromosome XV - NC_001147.6Genomic Context describing neighboring genes Neighboring gene Arf family GTPase ARF3 Neighboring gene ribose-5-phosphate isomerase RKI1 Neighboring gene uncharacterized protein Neighboring gene FG-nucleoporin NUP1

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_001147.6

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. The yeast ribosomal protein S7 and its genes. Synetos D, et al. J Biol Chem, 1992 Feb 15. PMID 1737755
  2. Ribosomal protein S7 ubiquitination during ER stress in yeast is associated with selective mRNA translation and stress outcome. Matsuki Y, et al. Sci Rep, 2020 Nov 12. PMID 33184379, Free PMC Article
  3. SIR2-induced inviability is suppressed by histone H4 overexpression. Matecic M, et al. Genetics, 2002 Oct. PMID 12399404, Free PMC Article
  4. Structure of the no-go mRNA decay complex Dom34-Hbs1 bound to a stalled 80S ribosome. Becker T, et al. Nat Struct Mol Biol, 2011 Jun. PMID 21623367
  5. The ubiquitination-deubiquitination cycle on the ribosomal protein eS7A is crucial for efficient translation. Takehara Y, et al. iScience, 2021 Mar 19. PMID 33665564, Free PMC Article

See all (120) citations in PubMed

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by SGD

Function Evidence Code Pubs
enables structural constituent of ribosome IEA
Inferred from Electronic Annotation
more info
  
enables structural constituent of ribosome NAS
Non-traceable Author Statement
more info
 PubMed 
Process Evidence Code Pubs
involved_in cytoplasmic translation NAS
Non-traceable Author Statement
more info
 PubMed 
involved_in rRNA processing IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in rRNA processing IEA
Inferred from Electronic Annotation
more info
  
involved_in ribosomal small subunit biogenesis IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in ribosome biogenesis IEA
Inferred from Electronic Annotation
more info
  
involved_in ribosome biogenesis IGI
Inferred from Genetic Interaction
more info
 PubMed 
involved_in translation IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
part_of 90S preribosome HDA PubMed 
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  
part_of cytosolic small ribosomal subunit IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of cytosolic small ribosomal subunit NAS
Non-traceable Author Statement
more info
 PubMed 
located_in nucleolus IEA
Inferred from Electronic Annotation
more info
  
located_in nucleus IEA
Inferred from Electronic Annotation
more info
  
part_of ribonucleoprotein complex IEA
Inferred from Electronic Annotation
more info
  
located_in ribosome IEA
Inferred from Electronic Annotation
more info
  
part_of small-subunit processome IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of small-subunit processome IDA
Inferred from Direct Assay
more info
 PubMed 

General protein information

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Preferred Names
ribosomal 40S subunit protein S7A
NP_014739.1
  • Protein component of the small (40S) ribosomal subunit; interacts with Kti11p; deletion causes hypersensitivity to zymocin; homologous to mammalian ribosomal protein S7, no bacterial homolog; RPS7A has a paralog, RPS7B, that arose from the whole genome duplication

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001147.6 Reference assembly

    Range
    505794..506767
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001183515.1 → NP_014739.1  TPA: ribosomal 40S subunit protein S7A [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_014739.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    D6W2F7, P26786, Q08502
    UniProtKB/TrEMBL
    A6ZNU6, B3LJE2, C7GMN8, C8ZI57, G2WMX3, N1NYD4
    Conserved Domains (1) summary
    pfam01251
    Location:6 → 186
    Ribosomal_S7e; Ribosomal protein S7e
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P26786.4

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