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ETT1 Ett1p [ Saccharomyces cerevisiae S288C ]

Gene ID: 854216, updated on 2-Nov-2024

Summary

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Official Symbol
ETT1
Official Full Name
Ett1p
Primary source
SGD:S000005577
Locus tag
YOR051C
See related
AllianceGenome:SGD:S000005577; FungiDB:YOR051C; VEuPathDB:YOR051C
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Also known as
NRO1; YOR29-02
Summary
Involved in translational termination. Located in nucleus. [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See ETT1 in Genome Data Viewer
Location:
chromosome: XV
Exon count:
1
Sequence:
Chromosome: XV; NC_001147.6 (424846..426084, complement)

Chromosome XV - NC_001147.6Genomic Context describing neighboring genes Neighboring gene ssRNA exonuclease RAT1 Neighboring gene phospholipid-translocating ATPase RSB1 Neighboring gene Tmc1p Neighboring gene phosphopantothenoylcysteine decarboxylase complex subunit VHS3

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_001147.6

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Structural and functional insights into Saccharomyces cerevisiae Tpa1, a putative prolylhydroxylase influencing translation termination and transcription. Henri J, et al. J Biol Chem, 2010 Oct 1. PMID 20630870, Free PMC Article
  2. Structural and functional analysis of Nro1/Ett1: a protein involved in translation termination in S. cerevisiae and in O2-mediated gene control in S. pombe. Rispal D, et al. RNA, 2011 Jul. PMID 21610214, Free PMC Article
  3. Reversible, Specific, Active Aggregates of Endogenous Proteins Assemble upon Heat Stress. Wallace EW, et al. Cell, 2015 Sep 10. PMID 26359986, Free PMC Article
  4. Systematic, genome-wide identification of host genes affecting replication of a positive-strand RNA virus. Kushner DB, et al. Proc Natl Acad Sci U S A, 2003 Dec 23. PMID 14671320, Free PMC Article
  5. Stm1p, a G4 quadruplex and purine motif triplex nucleic acid-binding protein, interacts with ribosomes and subtelomeric Y' DNA in Saccharomyces cerevisiae. Van Dyke MW, et al. J Biol Chem, 2004 Jun 4. PMID 15044472

See all (46) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Nro1/Ett1 unexpectedly adopts a Tetratrico Peptide Repeat (TPR) fold, a motif often responsible for protein or peptide binding.
    Title: Structural and functional analysis of Nro1/Ett1: a protein involved in translation termination in S. cerevisiae and in O2-mediated gene control in S. pombe.
Submit: New GeneRIF Correction

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by SGD

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in positive regulation of SREBP signaling pathway IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in regulation of translation IEA
Inferred from Electronic Annotation
more info
  
involved_in translational termination IGI
Inferred from Genetic Interaction
more info
 PubMed 
involved_in translational termination IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
located_in nucleus HDA PubMed 
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in nucleus IDA
Inferred from Direct Assay
more info
 PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
Ett1p
NP_014694.1
  • Nuclear protein that inhibits replication of Brome mosaic virus; S. cerevisiae is a model system for studying replication of positive-strand RNA viruses in their natural hosts; deletion increases stop codon readthrough

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001147.6 Reference assembly

    Range
    424846..426084 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001183470.1 → NP_014694.1  TPA: Ett1p [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_014694.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    C7GLH8, D6W2B6, O00016, Q08421, Q6Q5I2
    UniProtKB/TrEMBL
    G2WMT1, N1P300
    Conserved Domains (1) summary
    pfam12753
    Location:1 → 410
    Nro1; Nuclear pore complex subunit Nro1
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q08421.1

Gene LinkOut

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