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UTP11 [ Saccharomyces cerevisiae S288C ]

Gene ID: 853762, updated on 11-Sep-2024

Summary

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Official Symbol
UTP11
Primary source
SGD:S000001582
Locus tag
YKL099C
See related
AllianceGenome:SGD:S000001582; FungiDB:YKL099C; VEuPathDB:YKL099C
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Summary
Involved in endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); and endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA). Located in nucleolus. Part of small-subunit processome. Orthologous to human UTP11 (UTP11 small subunit processome component). [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

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Location:
chromosome: XI
Exon count:
1
Sequence:
Chromosome: XI; NC_001143.9 (255720..256472, complement)

Chromosome XI - NC_001143.9Genomic Context describing neighboring genes Neighboring gene protein kinase HSL1 Neighboring gene aspartic endopeptidase Neighboring gene Mtc2p Neighboring gene uncharacterized protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_001143.9

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. The complete structure of the small-subunit processome. Barandun J, et al. Nat Struct Mol Biol, 2017 Nov. PMID 28945246
  2. Yeast Rrp14p is a nucleolar protein involved in both ribosome biogenesis and cell polarity. Yamada H, et al. RNA, 2007 Nov. PMID 17804645, Free PMC Article
  3. Analysis of the Physiological Activities of Scd6 through Its Interaction with Hmt1. Lien PT, et al. PLoS One, 2016. PMID 27776129, Free PMC Article
  4. The small subunit processome is required for cell cycle progression at G1. Bernstein KA, et al. Mol Biol Cell, 2004 Nov. PMID 15356263, Free PMC Article
  5. RNA polymerase I transcription and pre-rRNA processing are linked by specific SSU processome components. Gallagher JE, et al. Genes Dev, 2004 Oct 15. PMID 15489292, Free PMC Article

See all (41) citations in PubMed

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by SGD

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA) IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in rRNA processing IEA
Inferred from Electronic Annotation
more info
  
involved_in ribosome biogenesis IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
is_active_in nucleolus IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in nucleolus IDA
Inferred from Direct Assay
more info
 PubMed 
located_in nucleolus IEA
Inferred from Electronic Annotation
more info
  
located_in nucleus IEA
Inferred from Electronic Annotation
more info
  
part_of ribonucleoprotein complex IEA
Inferred from Electronic Annotation
more info
  
part_of small-subunit processome IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of small-subunit processome IDA
Inferred from Direct Assay
more info
 PubMed 
part_of small-subunit processome IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
rRNA-processing protein UTP11
NP_012823.2
  • Subunit of U3-containing Small Subunit (SSU) processome complex; involved in production of 18S rRNA and assembly of small ribosomal subunit

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001143.9 Reference assembly

    Range
    255720..256472 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001179665.1 → NP_012823.2  TPA: rRNA-processing protein UTP11 [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_012823.2

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    A6ZZL7, B5VM59, D6VXI8, P34247
    UniProtKB/TrEMBL
    C7GVL1, C8ZC76, G2WHT4, N1P278
    Conserved Domains (1) summary
    COG5223
    Location:1 → 250
    COG5223; Uncharacterized conserved protein [Function unknown]
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P34247.2

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