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SEG2 Seg2p [ Saccharomyces cerevisiae S288C ]

Gene ID: 853756, updated on 2-Nov-2024

Summary

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Official Symbol
SEG2
Official Full Name
Seg2p
Primary source
SGD:S000001588
Locus tag
YKL105C
See related
AllianceGenome:SGD:S000001588; FungiDB:YKL105C; VEuPathDB:YKL105C
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Summary
Located in cell periphery. [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See SEG2 in Genome Data Viewer
Location:
chromosome: XI
Exon count:
1
Sequence:
Chromosome: XI; NC_001143.9 (239185..242583, complement)

Chromosome XI - NC_001143.9Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene aspartate transaminase AAT1 Neighboring gene glutamine--fructose-6-phosphate transaminase (isomerizing) GFA1 Neighboring gene uncharacterized protein Neighboring gene metalloaminopeptidase APE1

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_001143.9

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Formation and stability of eisosomes in the filamentous fungus Ashbya gossypii. Seger S, et al. J Cell Sci, 2011 May 15. PMID 21525038
  2. Molecular evolution of minisatellites in hemiascomycetous yeasts. Richard GF, et al. Mol Biol Evol, 2006 Jan. PMID 16177231
  3. Seg1 controls eisosome assembly and shape. Moreira KE, et al. J Cell Biol, 2012 Aug 6. PMID 22869600, Free PMC Article
  4. A role for eisosomes in maintenance of plasma membrane phosphoinositide levels. Fröhlich F, et al. Mol Biol Cell, 2014 Sep 15. PMID 25057013, Free PMC Article
  5. Quantitative Analysis of Dynamic Protein Interactions during Transcription Reveals a Role for Casein Kinase II in Polymerase-associated Factor (PAF) Complex Phosphorylation and Regulation of Histone H2B Monoubiquitylation. Bedard LG, et al. J Biol Chem, 2016 Jun 24. PMID 27143358, Free PMC Article

See all (26) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by SGD

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
  
Component Evidence Code Pubs
located_in cell periphery HDA PubMed 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
Seg2p
NP_012817.1
  • Eisosome component; likely plays only a minor role in eisosome assembly; shown to interact with Seg1p by affinity purification and mass spec; SWAT-GFP and mCherry fusion proteins localize to the cell periphery; similar to A. gossypii SEG gene which is important for stabilizing eisosomes; SEG2 has a paralog, SEG1, that arose from the whole genome duplication

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001143.9 Reference assembly

    Range
    239185..242583 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001179671.1 → NP_012817.1  TPA: Seg2p [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_012817.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    D6VXI3, P34250
    UniProtKB/TrEMBL
    A6ZZL2, G2WHS9
    Conserved Domains (1) summary
    PRK03918
    Location:293 → 383
    PRK03918; DNA double-strand break repair ATPase Rad50
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P34250.1

Gene LinkOut

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