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RPS4A ribosomal 40S subunit protein S4A [ Saccharomyces cerevisiae S288C ]

Gene ID: 853610, updated on 3-Nov-2024

Summary

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Official Symbol
RPS4A
Official Full Name
ribosomal 40S subunit protein S4A
Primary source
SGD:S000003906
Locus tag
YJR145C
See related
AllianceGenome:SGD:S000003906; FungiDB:YJR145C; VEuPathDB:YJR145C
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Summary
A structural constituent of ribosome. Predicted to be involved in translation. Located in cytoplasm. Part of cytosolic small ribosomal subunit. Orthologous to human RPS4X (ribosomal protein S4 X-linked); RPS4Y1 (ribosomal protein S4 Y-linked 1); and RPS4Y2 (ribosomal protein S4 Y-linked 2). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See RPS4A in Genome Data Viewer
Location:
chromosome: X
Exon count:
2
Sequence:
Chromosome: X; NC_001142.9 (702027..703068, complement)

Chromosome X - NC_001142.9Genomic Context describing neighboring genes Neighboring gene dolichyl-phosphate-mannose-protein mannosyltransferase Neighboring gene Mgm101p Neighboring gene uncharacterized protein Neighboring gene Hms2p Neighboring gene branched-chain-amino-acid transaminase BAT2

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_001142.9

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. The yeast ribosomal protein S7 and its genes. Synetos D, et al. J Biol Chem, 1992 Feb 15. PMID 1737755
  2. Secondary structure is required for 3' splice site recognition in yeast. Gahura O, et al. Nucleic Acids Res, 2011 Dec. PMID 21893588, Free PMC Article
  3. Saccharomyces cerevisiae coordinates accumulation of yeast ribosomal proteins by modulating mRNA splicing, translational initiation, and protein turnover. Warner JR, et al. Mol Cell Biol, 1985 Jun. PMID 3897837, Free PMC Article
  4. Transcription mediated insulation and interference direct gene cluster expression switches. Nguyen T, et al. Elife, 2014 Nov 19. PMID 25407679, Free PMC Article
  5. The transcription factor Ace2 and its paralog Swi5 regulate ethanol production during static fermentation through their targets Cts1 and Rps4a in Saccharomyces cerevisiae. Wu Y, et al. FEMS Yeast Res, 2016 May. PMID 26975390

See all (123) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by SGD

Function Evidence Code Pubs
enables RNA binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables RNA binding IEA
Inferred from Electronic Annotation
more info
  
enables rRNA binding IEA
Inferred from Electronic Annotation
more info
  
enables structural constituent of ribosome IBA
Inferred from Biological aspect of Ancestor
more info
  
enables structural constituent of ribosome IDA
Inferred from Direct Assay
more info
 PubMed 
enables structural constituent of ribosome IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in cytoplasmic translation IC
Inferred by Curator
more info
 PubMed 
involved_in translation IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in translation IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
part_of 90S preribosome HDA PubMed 
located_in cytoplasm HDA PubMed 
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  
part_of cytosolic small ribosomal subunit IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of cytosolic small ribosomal subunit IDA
Inferred from Direct Assay
more info
 PubMed 
located_in intracellular non-membrane-bounded organelle IEA
Inferred from Electronic Annotation
more info
  
part_of protein-containing complex IEA
Inferred from Electronic Annotation
more info
  
part_of ribonucleoprotein complex IEA
Inferred from Electronic Annotation
more info
  
located_in ribosome IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
ribosomal 40S subunit protein S4A
NP_012679.3
  • Protein component of the small (40S) ribosomal subunit; mutation affects 20S pre-rRNA processing; homologous to mammalian ribosomal protein S4, no bacterial homolog; RPS4A has a paralog, RPS4B, that arose from the whole genome duplication

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001142.9 Reference assembly

    Range
    702027..703068 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001181803.3 → NP_012679.3  TPA: ribosomal 40S subunit protein S4A [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_012679.3

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    D3DLF2, P05753, P0CX35, P0CX36
    UniProtKB/TrEMBL
    A6ZQA2, B3LQM5, C8ZA04, G2WFS7, N1P4X8
    Conserved Domains (1) summary
    PLN00036
    Location:1 → 259
    PLN00036; 40S ribosomal protein S4; Provisional
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P0CX35.1
P0CX36.1

Gene LinkOut

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Research Materials
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