SIP4 Sip4p [Saccharomyces cerevisiae S288C] - Gene

Summary

Official Symbol: SIP4
Official Full Name: Sip4p
Primary source: SGD:S000003625
Locus tag: YJL089W
See related: AllianceGenome:SGD:S000003625; FungiDB:YJL089W; VEuPathDB:YJL089W
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Saccharomyces cerevisiae S288C (strain: S288C)
Lineage: Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Summary: Enables DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in negative regulation of invasive growth in response to glucose limitation; positive regulation of gluconeogenesis; and positive regulation of transcription from RNA polymerase II promoter by a nonfermentable carbon source. Located in nucleus. [provided by Alliance of Genome Resources, Nov 2024]
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Chromosome X - NC_001142.9 Genomic Context describing neighboring genes

Go to nucleotide: Graphics FASTA GenBank

Two homologs of the Cat8 transcription factor are involved in the regulation of ethanol utilization in Komagataella phaffii.
Title: Two homologs of the Cat8 transcription factor are involved in the regulation of ethanol utilization in Komagataella phaffii.

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

Function	Evidence Code	Pubs
enables DNA binding	IEA Inferred from Electronic Annotation more info
enables DNA-binding transcription activator activity, RNA polymerase II-specific	IDA Inferred from Direct Assay more info	PubMed
enables DNA-binding transcription factor activity, RNA polymerase II-specific	IBA Inferred from Biological aspect of Ancestor more info
enables DNA-binding transcription factor activity, RNA polymerase II-specific	IEA Inferred from Electronic Annotation more info
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding	IDA Inferred from Direct Assay more info	PubMed
enables metal ion binding	IEA Inferred from Electronic Annotation more info
enables sequence-specific DNA binding	HDA more info	PubMed
enables sequence-specific DNA binding	IBA Inferred from Biological aspect of Ancestor more info
enables zinc ion binding	IEA Inferred from Electronic Annotation more info
enables zinc ion binding	RCA inferred from Reviewed Computational Analysis more info	PubMed

Process	Evidence Code	Pubs
involved_in negative regulation of invasive growth in response to glucose limitation	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in positive regulation of gluconeogenesis	IGI Inferred from Genetic Interaction more info	PubMed
involved_in positive regulation of gluconeogenesis	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in positive regulation of gluconeogenesis	IPI Inferred from Physical Interaction more info	PubMed
involved_in positive regulation of transcription by RNA polymerase II	IBA Inferred from Biological aspect of Ancestor more info
involved_in positive regulation of transcription by RNA polymerase II	IGI Inferred from Genetic Interaction more info	PubMed
involved_in positive regulation of transcription by RNA polymerase II	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in positive regulation of transcription from RNA polymerase II promoter by a nonfermentable carbon source	IGI Inferred from Genetic Interaction more info	PubMed
involved_in positive regulation of transcription from RNA polymerase II promoter by a nonfermentable carbon source	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in regulation of DNA-templated transcription	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in nucleus	IDA Inferred from Direct Assay more info	PubMed
located_in nucleus	IEA Inferred from Electronic Annotation more info

NP_012446.1

C6 zinc cluster transcriptional activator; binds to the carbon source-responsive element (CSRE) of gluconeogenic genes; involved in the positive regulation of gluconeogenesis; regulated by Snf1p protein kinase; localized to the nucleus

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