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RPA34 DNA-directed RNA polymerase I subunit RPA34 [ Saccharomyces cerevisiae S288C ]

Gene ID: 853293, updated on 18-Sep-2024

Summary

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Official Symbol
RPA34
Official Full Name
DNA-directed RNA polymerase I subunit RPA34
Primary source
SGD:S000003684
Locus tag
YJL148W
See related
AllianceGenome:SGD:S000003684; FungiDB:YJL148W; VEuPathDB:YJL148W
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Also known as
CST21
Summary
Contributes to RNA polymerase I activity. Involved in nucleolar large rRNA transcription by RNA polymerase I and transcription elongation from RNA polymerase I promoter. Located in nucleolus. Part of RNA polymerase I complex. [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

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See RPA34 in Genome Data Viewer
Location:
chromosome: X
Exon count:
1
Sequence:
Chromosome: X; NC_001142.9 (140437..141138)

Chromosome X - NC_001142.9Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene Smt1p Neighboring gene Ids2p

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_001142.9

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Further characterization of yeast RNA polymerases. Effect of subunits removal. Huet J, et al. Biochimie, 1976. PMID 182285
  2. Characterization of ribonuclease H activity associated yeast RNA polymerase A. Huet J, et al. J Biol Chem, 1977 Dec 25. PMID 21884
  3. Prefoldin-like Bud27 influences the transcription of ribosomal components and ribosome biogenesis in Saccharomyces cerevisiae. Martínez-Fernández V, et al. RNA, 2020 Oct. PMID 32503921, Free PMC Article
  4. Deletion of Rnt1p alters the proportion of open versus closed rRNA gene repeats in yeast. Catala M, et al. Mol Cell Biol, 2008 Jan. PMID 17991894, Free PMC Article
  5. Localization of the yeast RNA polymerase I-specific subunits. Bischler N, et al. EMBO J, 2002 Aug 1. PMID 12145213, Free PMC Article

See all (110) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by SGD

Function Evidence Code Pubs
contributes_to RNA polymerase I activity IDA
Inferred from Direct Assay
more info
 PubMed 
Process Evidence Code Pubs
involved_in nucleolar large rRNA transcription by RNA polymerase I IGI
Inferred from Genetic Interaction
more info
 PubMed 
involved_in ribosome biogenesis IEA
Inferred from Electronic Annotation
more info
  
involved_in transcription by RNA polymerase I IEA
Inferred from Electronic Annotation
more info
  
involved_in transcription elongation by RNA polymerase I IDA
Inferred from Direct Assay
more info
 PubMed 
Component Evidence Code Pubs
part_of DNA-directed RNA polymerase complex IEA
Inferred from Electronic Annotation
more info
  
part_of RNA polymerase I complex IDA
Inferred from Direct Assay
more info
 PubMed 
part_of RNA polymerase I complex IMP
Inferred from Mutant Phenotype
more info
 PubMed 
located_in nucleolus IDA
Inferred from Direct Assay
more info
 PubMed 
located_in nucleolus IEA
Inferred from Electronic Annotation
more info
  
located_in nucleus IDA
Inferred from Direct Assay
more info
 PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
DNA-directed RNA polymerase I subunit RPA34
NP_012387.1
  • RNA polymerase I subunit A34.5; essential for nucleolar assembly and for high polymerase loading rate; nucleolar localization depends on Rpa49p

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001142.9 Reference assembly

    Range
    140437..141138
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001181581.1 → NP_012387.1  TPA: DNA-directed RNA polymerase I subunit RPA34 [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_012387.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    D6VW37, P47006
    UniProtKB/TrEMBL
    A6ZQI2, C7GPY3, D3UF52, N1P0G1
    Conserved Domains (1) summary
    pfam08208
    Location:52 → 198
    RNA_polI_A34; DNA-directed RNA polymerase I subunit RPA34.5
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P47006.1

Gene LinkOut

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