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RPL17B ribosomal 60S subunit protein L17B [ Saccharomyces cerevisiae S288C ]

Gene ID: 853262, updated on 3-Nov-2024

Summary

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Official Symbol
RPL17B
Official Full Name
ribosomal 60S subunit protein L17B
Primary source
SGD:S000003713
Locus tag
YJL177W
See related
AllianceGenome:SGD:S000003713; FungiDB:YJL177W; VEuPathDB:YJL177W
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Summary
A structural constituent of ribosome. Involved in cleavage in ITS2 between 5.8S rRNA and LSU-rRNA of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) and cytoplasmic translation. Part of cytosolic large ribosomal subunit and preribosome, large subunit precursor. Orthologous to human RPL17 (ribosomal protein L17). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See RPL17B in Genome Data Viewer
Location:
chromosome: X
Exon count:
2
Sequence:
Chromosome: X; NC_001142.9 (90786..91657)

Chromosome X - NC_001142.9Genomic Context describing neighboring genes Neighboring gene prefolding complex chaperone subunit Neighboring gene Atg27p Neighboring gene Swi3p Neighboring gene Kre9p

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_001142.9

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. A single N(1)-methyladenosine on the large ribosomal subunit rRNA impacts locally its structure and the translation of key metabolic enzymes. Sharma S, et al. Sci Rep, 2018 Aug 9. PMID 30093689, Free PMC Article
  2. A Cdc48 "Retrochaperone" Function Is Required for the Solubility of Retrotranslocated, Integral Membrane Endoplasmic Reticulum-associated Degradation (ERAD-M) Substrates. Neal S, et al. J Biol Chem, 2017 Feb 24. PMID 28077573, Free PMC Article
  3. Farnesol inhibits translation to limit growth and filamentation in C. albicans and S. cerevisiae. Egbe NE, et al. Microb Cell, 2017 Sep 4. PMID 28913344, Free PMC Article
  4. Tandem affinity purification revealed the hypusine-dependent binding of eukaryotic initiation factor 5A to the translating 80S ribosomal complex. Jao DL, et al. J Cell Biochem, 2006 Feb 15. PMID 16215987
  5. Ribosome assembly factors Pwp1 and Nop12 are important for folding of 5.8S rRNA during ribosome biogenesis in Saccharomyces cerevisiae. Talkish J, et al. Mol Cell Biol, 2014 May. PMID 24636992, Free PMC Article

See all (113) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by SGD

Function Evidence Code Pubs
enables structural constituent of ribosome IBA
Inferred from Biological aspect of Ancestor
more info
  
enables structural constituent of ribosome IDA
Inferred from Direct Assay
more info
 PubMed 
enables structural constituent of ribosome IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in cleavage in ITS2 between 5.8S rRNA and LSU-rRNA of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) IGI
Inferred from Genetic Interaction
more info
 PubMed 
involved_in cytoplasmic translation IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in cytoplasmic translation IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in translation IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  
part_of cytosolic large ribosomal subunit IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of cytosolic large ribosomal subunit IDA
Inferred from Direct Assay
more info
 PubMed 
part_of large ribosomal subunit IEA
Inferred from Electronic Annotation
more info
  
part_of preribosome, large subunit precursor IDA
Inferred from Direct Assay
more info
 PubMed 
part_of ribonucleoprotein complex IEA
Inferred from Electronic Annotation
more info
  
located_in ribosome IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
ribosomal 60S subunit protein L17B
NP_012358.1
  • Ribosomal 60S subunit protein L17B; required for processing of 27SB pre-rRNA and formation of stable 66S assembly intermediates; homologous to mammalian ribosomal protein L17 and bacterial L22; RPL17B has a paralog, RPL17A, that arose from the whole genome duplication

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001142.9 Reference assembly

    Range
    90786..91657
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001181610.1 → NP_012358.1  TPA: ribosomal 60S subunit protein L17B [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_012358.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    D6VW12, P46990
    UniProtKB/TrEMBL
    A6ZQF7, B3LPU8, C7GS03, C8ZB42, G2WGJ8, N1P3T4
    Conserved Domains (1) summary
    PTZ00178
    Location:1 → 184
    PTZ00178; 60S ribosomal protein L17; Provisional
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P46990.2

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