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PAC10 tubulin-binding prefolding complex subunit PAC10 [ Saccharomyces cerevisiae S288C ]

Gene ID: 852969, updated on 3-Nov-2024

Summary

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Official Symbol
PAC10
Official Full Name
tubulin-binding prefolding complex subunit PAC10
Primary source
SGD:S000003310
Locus tag
YGR078C
See related
AllianceGenome:SGD:S000003310; FungiDB:YGR078C; VEuPathDB:YGR078C
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Also known as
GIM2; PFD3; RKS2
Summary
Enables tubulin binding activity. Involved in tubulin complex assembly. Located in cytoplasm. Part of prefoldin complex. Used to study cancer. Orthologous to human VBP1 (VHL binding protein 1). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See PAC10 in Genome Data Viewer
Location:
chromosome: VII
Exon count:
1
Sequence:
Chromosome: VII; NC_001139.9 (639772..640371, complement)

Chromosome VII - NC_001139.9Genomic Context describing neighboring genes Neighboring gene mitochondrial 54S ribosomal protein YmL25 Neighboring gene Pex8p Neighboring gene uncharacterized protein Neighboring gene Twf1p

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_001139.9

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by SGD

Function Evidence Code Pubs
enables tubulin binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables tubulin binding IDA
Inferred from Direct Assay
more info
 PubMed 
Process Evidence Code Pubs
involved_in microtubule-based process IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in protein folding IEA
Inferred from Electronic Annotation
more info
  
involved_in tubulin complex assembly IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in tubulin complex assembly IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in cytoplasm IDA
Inferred from Direct Assay
more info
 PubMed 
part_of prefoldin complex IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of prefoldin complex IEA
Inferred from Electronic Annotation
more info
  
part_of prefoldin complex IPI
Inferred from Physical Interaction
more info
 PubMed 

General protein information

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Preferred Names
tubulin-binding prefolding complex subunit PAC10
NP_011592.3
  • Part of the heteromeric co-chaperone GimC/prefoldin complex; complex promotes efficient protein folding

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001139.9 Reference assembly

    Range
    639772..640371 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001181207.3 → NP_011592.3  TPA: tubulin-binding prefolding complex subunit PAC10 [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_011592.3

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    D6VUL0, P48363
    UniProtKB/TrEMBL
    A6ZV60, B3LIE8, B5VJ22, C7GXQ7, C8Z8X2, G2WEG2, N1P270
    Conserved Domains (1) summary
    pfam02996
    Location:48 → 177
    Prefoldin; Prefoldin subunit
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P48363.1

Gene LinkOut

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