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PEX8 Pex8p [ Saccharomyces cerevisiae S288C ]

Gene ID: 852968, updated on 3-Nov-2024

Summary

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Official Symbol
PEX8
Official Full Name
Pex8p
Primary source
SGD:S000003309
Locus tag
YGR077C
See related
AllianceGenome:SGD:S000003309; FungiDB:YGR077C; VEuPathDB:YGR077C
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Also known as
PAS6
Summary
Enables protein-macromolecule adaptor activity. Involved in protein import into peroxisome matrix. Part of peroxisomal importomer complex. [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See PEX8 in Genome Data Viewer
Location:
chromosome: VII
Exon count:
1
Sequence:
Chromosome: VII; NC_001139.9 (637744..639513, complement)

Chromosome VII - NC_001139.9Genomic Context describing neighboring genes Neighboring gene mRNA splicing protein SMD1 Neighboring gene U4/U6-U5 snRNP complex subunit PRP38 Neighboring gene mitochondrial 54S ribosomal protein YmL25 Neighboring gene tubulin-binding prefolding complex subunit PAC10 Neighboring gene uncharacterized protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_001139.9

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by SGD

Function Evidence Code Pubs
enables protein-macromolecule adaptor activity IDA
Inferred from Direct Assay
more info
 PubMed 
Process Evidence Code Pubs
involved_in peroxisome organization IEA
Inferred from Electronic Annotation
more info
  
involved_in protein import into peroxisome matrix IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
part_of peroxisomal importomer complex IDA
Inferred from Direct Assay
more info
 PubMed 
located_in peroxisomal matrix IEA
Inferred from Electronic Annotation
more info
  
located_in peroxisome IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
Pex8p
NP_011591.1
  • Intraperoxisomal organizer of the peroxisomal import machinery; organizes the formation of the importomer complex, bridging the docking complex with the RING finger complex; tightly associated with the lumenal face of the peroxisomal membrane; essential for peroxisome biogenesis; binds PTS1-signal receptor Pex5p, and PTS2-signal receptor Pex7p

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001139.9 Reference assembly

    Range
    637744..639513 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001181206.1 → NP_011591.1  TPA: Pex8p [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_011591.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    D6VUK9, P53248
    UniProtKB/TrEMBL
    A6ZV59, B3LIE9, B5VJ18, C8Z8X1
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P53248.1

Gene LinkOut

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