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STF2 ATPase-stabilizing factor family protein [ Saccharomyces cerevisiae S288C ]

Gene ID: 852891, updated on 2-Nov-2024

Summary

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Official Symbol
STF2
Official Full Name
ATPase-stabilizing factor family protein
Primary source
SGD:S000003240
Locus tag
YGR008C
See related
AllianceGenome:SGD:S000003240; FungiDB:YGR008C; VEuPathDB:YGR008C
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Summary
Involved in cellular response to desiccation. Located in cytoplasm. [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See STF2 in Genome Data Viewer
Location:
chromosome: VII
Exon count:
1
Sequence:
Chromosome: VII; NC_001139.9 (508110..508364, complement)

Chromosome VII - NC_001139.9Genomic Context describing neighboring genes Neighboring gene mRNA splicing protein PRP18 Neighboring gene ethanolamine-phosphate cytidylyltransferase Neighboring gene Sec9p Neighboring gene nicotinamide-nucleotide adenylyltransferase NMA2

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_001139.9

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Isolation of a gene for a regulatory 15-kDa subunit of mitochondrial F1F0-ATPase and construction of mutant yeast lacking the protein. Yoshida Y, et al. Eur J Biochem, 1990 Aug 28. PMID 2169416
  2. High hydrostatic pressure leads to free radicals accumulation in yeast cells triggering oxidative stress. Bravim F, et al. FEMS Yeast Res, 2016 Aug. PMID 27388472
  3. Simultaneous bindings of ATPase inhibitor and 9K protein to F1F0-ATPase in the presence of 15K protein in yeast mitochondria. Hashimoto T, et al. J Biochem, 1990 Jul. PMID 2172220
  4. Binding of an intrinsic ATPase inhibitor to the F(1)FoATPase in phosphorylating conditions of yeast mitochondria. Iwatsuki H, et al. J Biochem, 2000 Oct. PMID 11011137
  5. Activation of ATP hydrolysis by an uncoupler in mutant mitochondria lacking an intrinsic ATPase inhibitor in yeast. Ichikawa N, et al. J Biol Chem, 1990 Apr 15. PMID 2138617

See all (37) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by SGD

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in cellular response to desiccation IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IDA
Inferred from Direct Assay
more info
 PubMed 
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  
located_in mitochondrion IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
ATPase-stabilizing factor family protein
NP_011522.1
  • Protein involved in resistance to desiccation stress; Stf2p exhibits antioxidant properties, and its overexpression prevents ROS accumulation and apoptosis; binds to F0 sector of mitochondrial F1F0 ATPase in vitro and may modulate the inhibitory action of Inh1p and Stf1p; protein abundance increases in response to DNA replication stress; STF2 has a paralog, TMA10, that arose from the whole genome duplication

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001139.9 Reference assembly

    Range
    508110..508364 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001181137.1 → NP_011522.1  TPA: ATPase-stabilizing factor family protein [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_011522.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    D6VUE5, P16965, P89099
    UniProtKB/TrEMBL
    A6ZV00, C7GK78, C8Z8Q2, G2WEA1, N1P5N1
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P16965.2

Gene LinkOut

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