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LCL3 Lcl3p [ Saccharomyces cerevisiae S288C ]

Gene ID: 852795, updated on 2-Nov-2024

Summary

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Official Symbol
LCL3
Official Full Name
Lcl3p
Primary source
SGD:S000003053
Locus tag
YGL085W
See related
AllianceGenome:SGD:S000003053; FungiDB:YGL085W; VEuPathDB:YGL085W
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Summary
Predicted to enable endonuclease activity and metal ion binding activity. Located in mitochondrion. [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See LCL3 in Genome Data Viewer
Location:
chromosome: VII
Exon count:
1
Sequence:
Chromosome: VII; NC_001139.9 (349616..350440)

Chromosome VII - NC_001139.9Genomic Context describing neighboring genes Neighboring gene E2 ubiquitin-conjugating protein MMS2 Neighboring gene coiled-coil domain-containing protein MAD1 Neighboring gene O-acyltransferase Neighboring gene Scy1p

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_001139.9

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by SGD

Function Evidence Code Pubs
enables endonuclease activity IEA
Inferred from Electronic Annotation
more info
  
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
  
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
  
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
located_in mitochondrion HDA PubMed 
located_in mitochondrion IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
Lcl3p
NP_011430.1
  • hypothetical protein; mutant has long chronological lifespan; has homology to Staphylococcus aureus nuclease; GFP-fusion protein localizes to mitochondria; is induced in response to the DNA-damaging agent MMS

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001139.9 Reference assembly

    Range
    349616..350440
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001180950.1 → NP_011430.1  TPA: Lcl3p [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_011430.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    A6ZU94, B3LHF1, B5VIN9, C7GW31, C8Z8G3, D6VU59, P53153
    UniProtKB/TrEMBL
    G2WE14, N1P3J5
    Conserved Domains (1) summary
    pfam00565
    Location:149 → 261
    SNase; Staphylococcal nuclease homolog
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P53153.1

Gene LinkOut

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