U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

USE1 SNAP receptor USE1 [ Saccharomyces cerevisiae S288C ]

Gene ID: 852780, updated on 29-Jun-2024

Summary

Go to the top of the page Help
Gene symbol
USE1
Gene description
SNAP receptor USE1
Primary source
FungiDB:YGL098W
Locus tag
YGL098W
See related
SGD:S000003066; AllianceGenome:SGD:S000003066; VEuPathDB:YGL098W
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Also known as
SLT1
Summary
Enables SNAP receptor activity. Involved in retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum. Is integral component of cytoplasmic side of endoplasmic reticulum membrane. Part of SNARE complex. Orthologous to human USE1 (unconventional SNARE in the ER 1). [provided by Alliance of Genome Resources, Apr 2022]
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
See USE1 in Genome Data Viewer
Location:
chromosome: VII
Exon count:
1
Sequence:
Chromosome: VII; NC_001139.9 (317342..318079)

Chromosome VII - NC_001139.9Genomic Context describing neighboring genes Neighboring gene putative GTPase LSG1 Neighboring gene ncRNA Neighboring gene tRNA-His Neighboring gene Ran guanyl-nucleotide exchange factor

Genomic regions, transcripts, and products

Go to the top of the page Help
Genomic Sequence:
NC_001139.9

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. Assembly-hub function of ER-localized SNARE proteins in biogenesis of tombusvirus replication compartment. Sasvari Z, et al. PLoS Pathog, 2018 May. PMID 29746582, Free PMC Article
  2. Structural characterization of Tip20p and Dsl1p, subunits of the Dsl1p vesicle tethering complex. Tripathi A, et al. Nat Struct Mol Biol, 2009 Feb. PMID 19151722, Free PMC Article
  3. The dynamin-like GTPase Sey1p mediates homotypic ER fusion in S. cerevisiae. Anwar K, et al. J Cell Biol, 2012 Apr 16. PMID 22508509, Free PMC Article
  4. A structure-based mechanism for vesicle capture by the multisubunit tethering complex Dsl1. Ren Y, et al. Cell, 2009 Dec 11. PMID 20005805, Free PMC Article
  5. A SNARE required for retrograde transport to the endoplasmic reticulum. Burri L, et al. Proc Natl Acad Sci U S A, 2003 Aug 19. PMID 12893879, Free PMC Article

See all (34) citations in PubMed

GeneRIFs: Gene References Into Functions

Pathways from PubChem

Go to the top of the page

Interactions

Go to the top of the page Help
Products Interactant Other Gene Complex Source Pubs Description

General gene information

Go to the top of the page Help

Homology

Gene Ontology Provided by SGD

Function Evidence Code Pubs
enables SNAP receptor activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables SNAP receptor activity IMP
Inferred from Mutant Phenotype
more info
 PubMed 
enables SNAP receptor activity IPI
Inferred from Physical Interaction
more info
 PubMed 
Process Evidence Code Pubs
involved_in protein transport IEA
Inferred from Electronic Annotation
more info
  
involved_in retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in vesicle-mediated transport IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
part_of SNARE complex IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of SNARE complex IDA
Inferred from Direct Assay
more info
 PubMed 
located_in cytoplasmic side of endoplasmic reticulum membrane IDA
Inferred from Direct Assay
more info
 PubMed 
located_in endoplasmic reticulum HDA PubMed 
is_active_in endoplasmic reticulum IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in endoplasmic reticulum IEA
Inferred from Electronic Annotation
more info
  
located_in endoplasmic reticulum membrane IEA
Inferred from Electronic Annotation
more info
  
located_in membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

Go to the top of the page Help
Preferred Names
SNAP receptor USE1
NP_011417.1
  • Essential SNARE protein localized to the ER; involved in retrograde traffic from the Golgi to the ER and Sey1p-independent homotypic ER fusion; required for efficient nuclear fusion during mating; forms a complex with the SNAREs Sec22p, Sec20p and Ufe1p

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001139.9 Reference assembly

    Range
    317342..318079
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001180963.1 → NP_011417.1  TPA: SNAP receptor USE1 [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_011417.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    D6VU47, P53146
    UniProtKB/TrEMBL
    A0A6A5PUU0, A6ZU82, B3LHG3, B5VIM8, C7GM16, C8Z8F0, G2WE01, N1P349
    Conserved Domains (1) summary
    cd15860
    Location:151 → 210
    SNARE_USE1; SNARE motif of USE1
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P53146.1

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Other Literature Sources
Molecular Biology Databases
Research Materials
Tools
Miscellaneous