CDC43 protein geranylgeranyltransferase type I subunit CDC43 [Saccharomyces cerevisiae S288C] - Gene

Summary

Official Symbol: CDC43
Official Full Name: protein geranylgeranyltransferase type I subunit CDC43
Primary source: SGD:S000003123
Locus tag: YGL155W
See related: AllianceGenome:SGD:S000003123; FungiDB:YGL155W; VEuPathDB:YGL155W
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Saccharomyces cerevisiae S288C (strain: S288C)
Lineage: Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Also known as: CAL1
Summary: Enables CAAX-protein geranylgeranyltransferase activity. Involved in protein geranylgeranylation. Part of CAAX-protein geranylgeranyltransferase complex. Orthologous to human PGGT1B (protein geranylgeranyltransferase type I subunit beta). [provided by Alliance of Genome Resources, Apr 2022]
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Chromosome VII - NC_001139.9 Genomic Context describing neighboring genes

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

Function	Evidence Code	Pubs
enables CAAX-protein geranylgeranyltransferase activity	IDA Inferred from Direct Assay more info	PubMed
enables CAAX-protein geranylgeranyltransferase activity	IEA Inferred from Electronic Annotation more info
enables metal ion binding	IEA Inferred from Electronic Annotation more info
enables prenyltransferase activity	IEA Inferred from Electronic Annotation more info
enables protein geranylgeranyltransferase activity	IEA Inferred from Electronic Annotation more info
enables zinc ion binding	RCA inferred from Reviewed Computational Analysis more info	PubMed

Process	Evidence Code	Pubs
involved_in protein geranylgeranylation	IDA Inferred from Direct Assay more info	PubMed
involved_in protein geranylgeranylation	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
part_of CAAX-protein geranylgeranyltransferase complex	IBA Inferred from Biological aspect of Ancestor more info
part_of CAAX-protein geranylgeranyltransferase complex	IDA Inferred from Direct Assay more info	PubMed
part_of CAAX-protein geranylgeranyltransferase complex	IEA Inferred from Electronic Annotation more info
located_in cytoplasm	IEA Inferred from Electronic Annotation more info

NP_011360.1

Beta subunit of geranylgeranyltransferase type I; subunit of the Ram2p-Cdc43p heterodimer that catalyzes the geranylgeranylation of the cysteine residue in proteins containing a C-terminal CaaX sequence ending in Leu or Phe; has substrates important for morphogenesis

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The following sections contain reference sequences that belong to a specific genome build. Explain