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MTC3 Mtc3p [ Saccharomyces cerevisiae S288C ]

Gene ID: 852626, updated on 18-Sep-2024

Summary

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Official Symbol
MTC3
Official Full Name
Mtc3p
Primary source
SGD:S000003195
Locus tag
YGL226W
See related
AllianceGenome:SGD:S000003195; FungiDB:YGL226W; VEuPathDB:YGL226W
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Summary
Predicted to be involved in mitochondrial electron transport, cytochrome c to oxygen. Located in mitochondrion. [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

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See MTC3 in Genome Data Viewer
Location:
chromosome: VII
Exon count:
1
Sequence:
Chromosome: VII; NC_001139.9 (73340..73711)

Chromosome VII - NC_001139.9Genomic Context describing neighboring genes Neighboring gene glucose-induced degradation complex subunit VID30 Neighboring gene dolichyl-diphosphooligosaccharide--protein glycotransferase subunit Neighboring gene tRNA-Val Neighboring gene GDP-mannose transporter

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_001139.9

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Regulation of cytochrome c oxidase activity by modulation of the catalytic site. Schäfer J, et al. Sci Rep, 2018 Jul 30. PMID 30061583, Free PMC Article
  2. Overexpression screens identify conserved dosage chromosome instability genes in yeast and human cancer. Duffy S, et al. Proc Natl Acad Sci U S A, 2016 Sep 6. PMID 27551064, Free PMC Article
  3. Multiple pathways influence mitochondrial inheritance in budding yeast. Frederick RL, et al. Genetics, 2008 Feb. PMID 18245340, Free PMC Article
  4. Functional genomics analysis of the Saccharomyces cerevisiae iron responsive transcription factor Aft1 reveals iron-independent functions. Berthelet S, et al. Genetics, 2010 Jul. PMID 20439772, Free PMC Article
  5. Yeast genes that enhance the toxicity of a mutant huntingtin fragment or alpha-synuclein. Willingham S, et al. Science, 2003 Dec 5. PMID 14657499

See all (26) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by SGD

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
  
involved_in mitochondrial electron transport, cytochrome c to oxygen IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in mitochondrial electron transport, cytochrome c to oxygen IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in mitochondrion HDA PubMed 
located_in mitochondrion IEA
Inferred from Electronic Annotation
more info
  
part_of respiratory chain complex IV IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of respiratory chain complex IV IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
Mtc3p
NP_011289.1
  • hypothetical protein; green fluorescent protein (GFP)-fusion protein localizes to the mitochondrion; mtc3 is synthetically sick with cdc13-1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001139.9 Reference assembly

    Range
    73340..73711
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001181092.1 → NP_011289.1  TPA: Mtc3p [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_011289.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    D6VVA9, P53077
    UniProtKB/TrEMBL
    G2WDN4
    Conserved Domains (1) summary
    cl02792
    Location:25 → 109
    Cyt_c_Oxidase_IV; Cytochrome c oxidase subunit IV. Cytochrome c oxidase (CcO), the terminal oxidase in the respiratory chains of eukaryotes and most bacteria, is a multi-chain transmembrane protein located in the inner membrane of mitochondria and the cell membrane of ...
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P53077.1

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