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SHG1 Shg1p [ Saccharomyces cerevisiae S288C ]

Gene ID: 852561, updated on 3-Nov-2024

Summary

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Official Symbol
SHG1
Official Full Name
Shg1p
Primary source
SGD:S000000462
Locus tag
YBR258C
See related
AllianceGenome:SGD:S000000462; FungiDB:YBR258C; VEuPathDB:YBR258C
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Also known as
CPS15
Summary
Contributes to histone H3K4 methyltransferase activity. Involved in chromatin remodeling. Located in nucleus. Part of Set1C/COMPASS complex. [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See SHG1 in Genome Data Viewer
Location:
chromosome: II
Exon count:
1
Sequence:
Chromosome: II; NC_001134.8 (729734..730162, complement)

Chromosome II - NC_001134.8Genomic Context describing neighboring genes Neighboring gene riboflavin synthase Neighboring gene RNase P/RNase MRP complex subunit Neighboring gene uncharacterized protein Neighboring gene GTPase-activating protein RGD1

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_001134.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Cotranslational assembly of the yeast SET1C histone methyltransferase complex. Halbach A, et al. EMBO J, 2009 Oct 7. PMID 19713935, Free PMC Article
  2. Structural modeling of histone methyltransferase complex Set1C from Saccharomyces cerevisiae using constraint-based docking. Tuukkanen A, et al. Proteomics, 2010 Dec. PMID 21046623
  3. COMPASS, a histone H3 (Lysine 4) methyltransferase required for telomeric silencing of gene expression. Krogan NJ, et al. J Biol Chem, 2002 Mar 29. PMID 11805083
  4. Architecture and subunit arrangement of the complete Saccharomyces cerevisiae COMPASS complex. Wang Y, et al. Sci Rep, 2018 Nov 27. PMID 30479350, Free PMC Article
  5. Structure and Conformational Dynamics of a COMPASS Histone H3K4 Methyltransferase Complex. Qu Q, et al. Cell, 2018 Aug 23. PMID 30100186, Free PMC Article

See all (44) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by SGD

Function Evidence Code Pubs
contributes_to histone H3K4 methyltransferase activity IDA
Inferred from Direct Assay
more info
 PubMed 
Process Evidence Code Pubs
involved_in chromatin remodeling IDA
Inferred from Direct Assay
more info
 PubMed 
Component Evidence Code Pubs
part_of Set1C/COMPASS complex IPI
Inferred from Physical Interaction
more info
 PubMed 
located_in chromosome, telomeric region IEA
Inferred from Electronic Annotation
more info
  
located_in nucleus HDA PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
Shg1p
NP_009817.3
  • Subunit of the COMPASS (Set1C) complex; COMPASS methylates histone H3 on lysine 4 and is required in transcriptional silencing near telomeres

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001134.8 Reference assembly

    Range
    729734..730162 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001178606.3 → NP_009817.3  TPA: Shg1p [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_009817.3

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    D6VQQ5, P38337
    UniProtKB/TrEMBL
    A6ZLJ8, B3LMQ3, D3UF06, G2W9R3
    Conserved Domains (1) summary
    pfam05205
    Location:10 → 126
    COMPASS-Shg1; COMPASS (Complex proteins associated with Set1p) component shg1
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P38337.1

Gene LinkOut

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