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RPL19A ribosomal 60S subunit protein L19A [ Saccharomyces cerevisiae S288C ]

Gene ID: 852379, updated on 2-Nov-2024

Summary

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Official Symbol
RPL19A
Official Full Name
ribosomal 60S subunit protein L19A
Primary source
SGD:S000002156
Locus tag
YBR084C-A
See related
AllianceGenome:SGD:S000002156; FungiDB:YBR084C-A; VEuPathDB:YBR084C-A
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Summary
Predicted to enable RNA binding activity. Predicted to be a structural constituent of ribosome. Predicted to be involved in cytoplasmic translation. Part of cytosolic large ribosomal subunit. Orthologous to human RPL19 (ribosomal protein L19). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See RPL19A in Genome Data Viewer
Location:
chromosome: II
Exon count:
2
Sequence:
Chromosome: II; NC_001134.8 (414186..415261, complement)

Chromosome II - NC_001134.8Genomic Context describing neighboring genes Neighboring gene Tec1p Neighboring gene trifunctional formate-tetrahydrofolate ligase/methenyltetrahydrofolate cyclohydrolase/methylenetetrahydrofolate dehydrogenase MIS1 Neighboring gene ADP/ATP carrier protein AAC3 Neighboring gene uncharacterized protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_001134.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Nucleotide sequence and characterization of the Saccharomyces cerevisiae RPL19A gene encoding a homolog of the mammalian ribosomal protein L19. Song JM, et al. Yeast, 1995 Apr 15. PMID 7785339
  2. The Functional Role of eL19 and eB12 Intersubunit Bridge in the Eukaryotic Ribosome. Kisly I, et al. J Mol Biol, 2016 May 22. PMID 27038511, Free PMC Article
  3. Functional analysis of a duplicated linked pair of ribosomal protein genes in Saccharomyces cerevisiae. Donovan DM, et al. Mol Cell Biol, 1990 Nov. PMID 2233736, Free PMC Article
  4. Organization and characterization of the two yeast ribosomal protein YL19 genes. Song JM, et al. Curr Genet, 1996 Sep. PMID 8781168
  5. Functional Interactions of Ribosomal Intersubunit Bridges in Saccharomyces cerevisiae. Tamm T, et al. Genetics, 2019 Dec. PMID 31649153, Free PMC Article

See all (100) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by SGD

Function Evidence Code Pubs
enables RNA binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables RNA binding IEA
Inferred from Electronic Annotation
more info
  
enables structural constituent of ribosome IBA
Inferred from Biological aspect of Ancestor
more info
  
enables structural constituent of ribosome IC
Inferred by Curator
more info
 PubMed 
enables structural constituent of ribosome IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in cytoplasmic translation IC
Inferred by Curator
more info
 PubMed 
involved_in translation IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  
part_of cytosolic large ribosomal subunit IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of cytosolic large ribosomal subunit IDA
Inferred from Direct Assay
more info
 PubMed 
part_of cytosolic large ribosomal subunit IEA
Inferred from Electronic Annotation
more info
  
part_of ribonucleoprotein complex IEA
Inferred from Electronic Annotation
more info
  
located_in ribosome IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
ribosomal 60S subunit protein L19A
NP_009641.1
  • Ribosomal 60S subunit protein L19A; rpl19a and rpl19b single null mutations result in slow growth, while the double null mutation is lethal; homologous to mammalian ribosomal protein L19, no bacterial homolog; RPL19A has a paralog, RPL19B, that arose from the whole genome duplication

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001134.8 Reference assembly

    Range
    414186..415261 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001180057.1 → NP_009641.1  TPA: ribosomal 60S subunit protein L19A [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_009641.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    D6VPX3, P05735, P0CX82, P0CX83
    UniProtKB/TrEMBL
    A6ZKS1, B3LN67, C8Z3W9, G2W991
    Conserved Domains (1) summary
    cd01417
    Location:4 → 166
    Ribosomal_L19e_E; Ribosomal protein L19e, eukaryotic. L19e is found in the large ribosomal subunit of eukaryotes and archaea. L19e is distinct from the ribosomal subunit L19, which is found in prokaryotes. It consists of two small globular domains connected by an ...
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P0CX82.1
P0CX83.1

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