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LDB7 Ldb7p [ Saccharomyces cerevisiae S288C ]

Gene ID: 852277, updated on 2-Nov-2024

Summary

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Official Symbol
LDB7
Official Full Name
Ldb7p
Primary source
SGD:S000000102
Locus tag
YBL006C
See related
AllianceGenome:SGD:S000000102; FungiDB:YBL006C; VEuPathDB:YBL006C
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Also known as
RSC14
Summary
Involved in nucleosome disassembly and transcription elongation by RNA polymerase II. Part of RSC-type complex. [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See LDB7 in Genome Data Viewer
Location:
chromosome: II
Exon count:
1
Sequence:
Chromosome: II; NC_001134.8 (216587..217129, complement)

Chromosome II - NC_001134.8Genomic Context describing neighboring genes Neighboring gene Hir1p Neighboring gene cytoskeletal protein-binding protein SLA1 Neighboring gene drug-responsive transcription factor PDR3 Neighboring gene gag protein Neighboring gene gag-pol fusion protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_001134.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. The Rpd3-Complex Regulates Expression of Multiple Cell Surface Recycling Factors in Yeast. Amoiradaki K, et al. Int J Mol Sci, 2021 Nov 19. PMID 34830359, Free PMC Article
  2. Rsc14-controlled expression of MNN6, MNN4 and MNN1 regulates mannosylphosphorylation of Saccharomyces cerevisiae cell wall mannoproteins. Conde R, et al. FEMS Yeast Res, 2007 Dec. PMID 17627774
  3. Screening for new yeast mutants affected in mannosylphosphorylation of cell wall mannoproteins. Conde R, et al. Yeast, 2003 Oct 30. PMID 14587103
  4. RSC facilitates Rad59-dependent homologous recombination between sister chromatids by promoting cohesin loading at DNA double-strand breaks. Oum JH, et al. Mol Cell Biol, 2011 Oct. PMID 21807899, Free PMC Article
  5. The budding yeast RSC complex maintains ploidy by promoting spindle pole body insertion. Sing TL, et al. J Cell Biol, 2018 Jul 2. PMID 29875260, Free PMC Article

See all (61) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. ybl006c (Rsc14) controls expression of MNN6, MNN4 and MNN1
    Title: Rsc14-controlled expression of MNN6, MNN4 and MNN1 regulates mannosylphosphorylation of Saccharomyces cerevisiae cell wall mannoproteins.
Submit: New GeneRIF Correction

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by SGD

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in chromatin organization IEA
Inferred from Electronic Annotation
more info
  
involved_in chromatin remodeling IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in chromatin remodeling IEA
Inferred from Electronic Annotation
more info
  
involved_in nucleosome disassembly IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in transcription elongation by RNA polymerase II IDA
Inferred from Direct Assay
more info
 PubMed 
Component Evidence Code Pubs
part_of RSC-type complex IDA
Inferred from Direct Assay
more info
 PubMed 
part_of RSC-type complex IEA
Inferred from Electronic Annotation
more info
  
part_of RSC-type complex IGI
Inferred from Genetic Interaction
more info
 PubMed 
part_of RSC-type complex IMP
Inferred from Mutant Phenotype
more info
 PubMed 
part_of RSC-type complex IPI
Inferred from Physical Interaction
more info
 PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
Ldb7p
NP_009547.2
  • Component of the RSC chromatin remodeling complex; interacts with Rsc3p, Rsc30p, Npl6p, and Htl1p to form a module important for a broad range of RSC functions

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001134.8 Reference assembly

    Range
    216587..217129 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001178246.1 → NP_009547.2  TPA: Ldb7p [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_009547.2

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    D6VPZ4, P38210
    UniProtKB/TrEMBL
    G2W903
    Conserved Domains (1) summary
    pfam08586
    Location:7 → 106
    Rsc14; RSC complex, Rsc14/Ldb7 subunit
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P38210.2

Gene LinkOut

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